{"id":"W3210265530","doi":"10.1158/1055-9965.epi-21-0677","title":"DNA Methylation Profiles of Ovarian Clear Cell Carcinoma","year":2021,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Canadian Centre for Applied Research in Cancer Control; Vancouver General Hospital; University of British Columbia; Calgary Laboratory Services; BC Cancer Agency","funders":"National Cancer Institute; Cancer Research UK; Mayo Clinic; Cancer Institute NSW; American Cancer Society","keywords":"DNA methylation; Clear cell carcinoma; Clear cell; Methylation; Epigenetics; DNA; Carcinoma; Clear cell renal cell carcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009149558,0.0001569441,0.0002985383,0.00004300307,0.00006466964,0.000004196582,0.0001319994,0.0002891532,0.0001476957],"category_scores_gemma":[0.0002397628,0.0001598213,0.0002291619,0.0001242526,0.0001097188,0.000006346563,0.00008249357,0.00008263806,0.00000515284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004541891,"about_ca_system_score_gemma":0.0002769975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009457886,"about_ca_topic_score_gemma":0.00007048099,"domain_scores_codex":[0.998063,0.000606805,0.0005191992,0.000477092,0.00008102555,0.000252842],"domain_scores_gemma":[0.9989772,0.00005863223,0.0003449992,0.0003757394,0.0001761908,0.00006726304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002572481,0.00008231914,0.04042936,0.0001580354,0.0001861432,0.000001640112,0.00003729867,0.0003068766,0.9333382,0.0001508908,0.007086347,0.01796569],"study_design_scores_gemma":[0.001090261,0.0002548759,0.06179961,0.00008880858,0.0001363841,0.00000997994,0.0001234966,0.001106967,0.9245701,0.002539601,0.008000501,0.0002793939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9644589,0.02054191,0.01262397,0.0007100266,0.00052091,0.0002053031,0.00002990981,0.0000166126,0.0008924667],"genre_scores_gemma":[0.9905148,0.0009388,0.006439886,0.0002252204,0.0002355419,0.00006002373,0.0004504566,0.00002278307,0.001112536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02605586,"threshold_uncertainty_score":0.6517324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03511234553547427,"score_gpt":0.3287978691532112,"score_spread":0.293685523617737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}