{"id":"W3210492059","doi":"10.1097/mcg.0000000000001626","title":"Fucosyltransferase 2 Mutations Are Associated With a Favorable Clinical Course in Crohn’s Disease","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"","keywords":"Medicine; Internal medicine; Gastroenterology; Crohn's disease; Odds ratio; Allele; Fucosyltransferase; Nonsense mutation; Confidence interval; Compound heterozygosity; Immunology; Disease; Mutation; Missense mutation; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004209023,0.000390791,0.0003194505,0.0005034737,0.0004319215,0.000427453,0.000244176,0.0006630291,0.003582835],"category_scores_gemma":[0.00199812,0.0001873072,0.0003589008,0.0006320854,0.0003295483,0.0002175797,0.0003099547,0.0005883023,0.0002420025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001217894,"about_ca_system_score_gemma":0.0001577208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006293344,"about_ca_topic_score_gemma":0.0008126945,"domain_scores_codex":[0.9997017,0.00008279884,0.00003502522,0.00008949549,0.0000487421,0.00004223699],"domain_scores_gemma":[0.9983564,0.0003641338,0.0008297968,0.00007271631,0.00007781652,0.0002991716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003683443,0.00003404146,0.997053,0.000009342031,0.00004429474,0.0002755767,0.00003158076,0.00003117689,0.0009566884,0.00001422405,0.00005689553,0.0011247],"study_design_scores_gemma":[0.00001403613,0.00009577372,0.9981486,0.000007020175,0.00004672895,0.001243648,0.00003953011,0.0001627051,0.0001063474,0.00003881487,0.00009371345,0.000003151595],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994277,0.0001954073,0.00005731069,0.0000374257,0.000005286134,0.00000222157,0.00005675612,0.000003761874,0.0002142665],"genre_scores_gemma":[0.9997275,0.00004551248,0.0000743409,0.0000126135,0.00001314343,0.000002092554,0.00006425171,0.000001685299,0.0000589201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003582835,"threshold_uncertainty_score":0.01198578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02504411304656731,"score_gpt":0.3399853049952896,"score_spread":0.3149411919487223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}