{"id":"W3210614912","doi":"10.1038/s41591-021-01503-6","title":"Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy","year":2021,"lang":"en","type":"article","venue":"Nature Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Maple Leaf Medical Clinic","funders":"National Institute of Allergy and Infectious Diseases; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Human immunodeficiency virus (HIV); Antiretroviral therapy; Medicine; Drug holiday; Virology; Term (time); Immunology; Viral load; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002237138,0.0002015139,0.0006217426,0.0002030567,0.00002498003,0.000002291796,0.00009909941,0.000278651,0.001555642],"category_scores_gemma":[0.0001227232,0.0001219902,0.00009781962,0.0002169349,0.0002365774,0.00003324772,0.00003193329,0.0003901263,0.0000375862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007975726,"about_ca_system_score_gemma":0.00007070209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000816828,"about_ca_topic_score_gemma":0.0002297415,"domain_scores_codex":[0.9985902,0.0003854493,0.0003655829,0.0002753724,0.00009429834,0.0002890365],"domain_scores_gemma":[0.9992521,0.0002028225,0.0001398115,0.0002642846,0.0001108892,0.00003002496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007218262,0.0007079605,0.5271328,0.00001849605,0.0004218466,0.0001990851,0.0002786135,4.426137e-7,0.4624582,0.0001109979,0.00004296938,0.007906768],"study_design_scores_gemma":[0.01665406,0.002310791,0.7897514,0.0001162019,0.00007833002,0.0000469385,0.00004177553,0.000001218546,0.1906643,0.0001245213,0.0001321518,0.0000783815],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857864,0.01211536,0.0004221328,0.0006689653,0.0002402652,0.0004003479,0.0002178253,0.00001761888,0.0001311027],"genre_scores_gemma":[0.9981302,0.0003771493,0.00002737558,0.0001604055,0.00003224803,0.00005584996,0.0009709166,0.00001033337,0.0002355423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2717939,"threshold_uncertainty_score":0.999357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01414758068601818,"score_gpt":0.319552046781192,"score_spread":0.3054044660951738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}