{"id":"W3210720681","doi":"10.14309/01.ajg.0000776312.86615.e5","title":"S695 Risankizumab Induces Early Clinical Remission and Response in Patients With Moderate-To-Severe Crohn’s Disease: Results From the Phase 3 ADVANCE and MOTIVATE Studies","year":2021,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Crohn's disease; Internal medicine; Placebo; Population; Gastroenterology; Clinical trial; Randomized controlled trial; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002999401,0.0006305904,0.00199282,0.0002884623,0.0002692683,0.000683192,0.000536244,0.0009549577,0.002199164],"category_scores_gemma":[0.00122879,0.0003429204,0.001507705,0.0002942875,0.000586466,0.0005238184,0.0003772536,0.00148517,0.0004506125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004307163,"about_ca_system_score_gemma":0.0008902806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005154769,"about_ca_topic_score_gemma":0.002353327,"domain_scores_codex":[0.9991707,0.0005010682,0.00006513114,0.00007358532,0.00009356487,0.00009595358],"domain_scores_gemma":[0.9989047,0.0002892721,0.0003340626,0.00008283358,0.00008788507,0.0003013253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.843147,0.02459044,0.01110191,0.001739505,0.002138657,0.0001318887,0.0002452084,0.0006081699,0.01814733,0.0002171542,0.002742157,0.0951905],"study_design_scores_gemma":[0.5343438,0.4125751,0.04500746,0.0001211388,0.001196278,0.0002737288,0.00006827337,0.000468745,0.002054898,0.0001555283,0.003690182,0.00004478143],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990576,0.006122366,0.0002171948,0.0003650125,0.00006553653,0.0007318614,0.0006089215,0.00005465484,0.001258468],"genre_scores_gemma":[0.9932089,0.002502933,0.0009154682,0.0006480878,0.0001985131,0.000595907,0.00118755,0.00001299525,0.000729538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002999401,"threshold_uncertainty_score":0.01586252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224774914199423,"score_gpt":0.2945188063132413,"score_spread":0.2822710571712471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}