{"id":"W3210721043","doi":"10.1182/blood-2021-148723","title":"Subcutaneous Teclistamab in Combination with Daratumumab for the Treatment of Patients with Relapsed/Refractory Multiple Myeloma: Results from a Phase 1b Multicohort Study","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Daratumumab; Internal medicine; Oncology; Phases of clinical research; Gastroenterology; Lenalidomide; Multiple myeloma; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002912529,0.001669613,0.002498017,0.000487302,0.0005395202,0.001196721,0.0007494297,0.001104708,0.002231896],"category_scores_gemma":[0.0009514001,0.0006369283,0.001754295,0.0005772895,0.0007070131,0.0009252853,0.0004130701,0.002501759,0.0007523022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001120192,"about_ca_system_score_gemma":0.001385101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001009307,"about_ca_topic_score_gemma":0.001877784,"domain_scores_codex":[0.9992467,0.0003566066,0.00005608719,0.0001375594,0.00009656567,0.000106422],"domain_scores_gemma":[0.999235,0.0001071229,0.0001682229,0.0000712188,0.00006520494,0.0003533171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6294574,0.1288559,0.01988957,0.001418189,0.006743534,0.0005639871,0.0004906931,0.002363364,0.05507739,0.0001519101,0.004120033,0.1508681],"study_design_scores_gemma":[0.4733566,0.4830861,0.03463114,0.00004923345,0.001920583,0.0004813415,0.00007856424,0.001009448,0.002824352,0.0001045367,0.00241447,0.00004362662],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934106,0.002909596,0.0004836205,0.0003212906,0.00008759613,0.001308089,0.0007748654,0.00006888454,0.0006353441],"genre_scores_gemma":[0.9924178,0.001692255,0.00124873,0.0008478901,0.0001883612,0.001063553,0.001599959,0.00002701758,0.0009144668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002912529,"threshold_uncertainty_score":0.01540309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02074947527204619,"score_gpt":0.2892408066175379,"score_spread":0.2684913313454917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}