{"id":"W3210899505","doi":"10.14309/01.ajg.0000776620.39225.48","title":"S772 Risankizumab Therapy Induces Improvements in Endoscopic Endpoints in Patients With Moderate-To-Severe Crohn’s Disease: Results From the Phase 3 ADVANCE and MOTIVATE Studies","year":2021,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Robarts Clinical Trials; Western University","funders":"","keywords":"Medicine; Internal medicine; Placebo; Crohn's disease; Gastroenterology; Population; Endoscopy; Colonoscopy; Clinical endpoint; Clinical trial; Randomized controlled trial; Disease; Surgery; Pathology; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00367628,0.0007777332,0.002301055,0.0003259476,0.0002594158,0.0008320255,0.0004634956,0.001114798,0.002774464],"category_scores_gemma":[0.002152564,0.0003822617,0.002677575,0.0003369543,0.0006684659,0.0006733128,0.0004640018,0.001252961,0.0004482998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004072446,"about_ca_system_score_gemma":0.0008401361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004038128,"about_ca_topic_score_gemma":0.001746222,"domain_scores_codex":[0.9986713,0.0008425344,0.00009890206,0.0001014931,0.0001604133,0.0001254142],"domain_scores_gemma":[0.9982487,0.0005567198,0.0005469244,0.0001365418,0.0001618222,0.0003493076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9146993,0.01179104,0.009892095,0.001175662,0.003467789,0.00007367765,0.0001473599,0.0004172374,0.008026057,0.0001272662,0.001261242,0.0489214],"study_design_scores_gemma":[0.5117904,0.4104292,0.06860984,0.0001465656,0.003108779,0.0001841605,0.00009879195,0.0005519777,0.001999826,0.000176155,0.002850629,0.00005370938],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924886,0.004589962,0.0001776832,0.000270788,0.00006124524,0.000624266,0.0005029015,0.00002700454,0.001257505],"genre_scores_gemma":[0.9942147,0.001929124,0.0006749288,0.000502451,0.0002418743,0.0005594945,0.001046329,0.00001064313,0.0008203976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00367628,"threshold_uncertainty_score":0.01944226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008487559195142833,"score_gpt":0.2586757707012775,"score_spread":0.2501882115061346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}