{"id":"W3210976641","doi":"10.1038/s42255-021-00481-w","title":"Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2","year":2021,"lang":"en","type":"article","venue":"Nature Metabolism","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; University of California, San Diego; National Institutes of Health; Vetenskapsrådet; Karolinska Institutet; Indiana Corn Marketing Council; American Heart Association","keywords":"Adipose tissue; Biology; Mitochondrion; Mitochondrial biogenesis; Locus (genetics); Mitochondrial DNA; Oxidative phosphorylation; Gene; Metabolic syndrome; Insulin resistance; Endocrinology; Internal medicine; Cell biology; Genetics; Insulin; Biochemistry; Diabetes mellitus; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002133359,0.0003702599,0.001198315,0.000235958,0.0000910575,0.00003321958,0.0001428294,0.000659774,0.000397551],"category_scores_gemma":[0.0001572022,0.0003321544,0.000211876,0.000713205,0.0001529284,0.0001680828,0.00009276569,0.0008014363,0.0000338126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001414758,"about_ca_system_score_gemma":0.0001345121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001607113,"about_ca_topic_score_gemma":0.000002848663,"domain_scores_codex":[0.9975055,0.0001650418,0.0005861585,0.000680488,0.0006375908,0.0004252317],"domain_scores_gemma":[0.9981986,0.00007810861,0.0002081234,0.0008104001,0.0003765104,0.0003282118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001214681,0.000306947,0.001321741,0.00014977,0.0005861667,0.0002635225,0.0005737739,0.000003045914,0.9132591,0.01312385,0.01350778,0.05678279],"study_design_scores_gemma":[0.001965248,0.00003378131,0.214626,0.00005174842,0.0008351408,0.001222002,0.0000613675,0.00002037118,0.1989162,0.0008331974,0.5811797,0.0002553125],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5661585,0.4309016,0.0001870899,0.0005461008,0.0008394943,0.000349542,0.00006253568,0.0000573391,0.0008978125],"genre_scores_gemma":[0.9649127,0.0103994,0.01283129,0.0007737365,0.0007193531,0.00002658336,0.0001916107,0.00008576519,0.01005957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.714343,"threshold_uncertainty_score":0.999913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007889642086042651,"score_gpt":0.2464054726094345,"score_spread":0.2385158305233918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}