{"id":"W3210976641","doi":"10.1038/s42255-021-00481-w","title":"Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2","year":2021,"lang":"en","type":"article","venue":"Nature Metabolism","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; University of California, San Diego; National Institutes of Health; Vetenskapsrådet; Karolinska Institutet; Indiana Corn Marketing Council; American Heart Association","keywords":"Adipose tissue; Biology; Mitochondrion; Mitochondrial biogenesis; Locus (genetics); Mitochondrial DNA; Oxidative phosphorylation; Gene; Metabolic syndrome; Insulin resistance; Endocrinology; Internal medicine; Cell biology; Genetics; Insulin; Biochemistry; Diabetes mellitus; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001444865,0.0003519506,0.0002286414,0.0004632816,0.0001808532,0.0003133818,0.0002706966,0.0003178156,0.003846477],"category_scores_gemma":[0.0003118291,0.0002196076,0.0002764216,0.000185045,0.0002745989,0.0001633899,0.0003610441,0.0003021372,0.0002116417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002353193,"about_ca_system_score_gemma":0.0001384672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009728645,"about_ca_topic_score_gemma":0.001572178,"domain_scores_codex":[0.9998443,0.00003557996,0.00001499458,0.00004426106,0.00002850121,0.00003226048],"domain_scores_gemma":[0.9997835,0.00004262854,0.00007855475,0.0000276957,0.00001494769,0.00005283814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001233295,0.00003943391,0.007527243,0.00002617395,0.00005887499,0.0005429221,0.00008779671,0.0001123081,0.9858645,0.0007859692,0.000183174,0.003538311],"study_design_scores_gemma":[0.0003235699,0.0005881532,0.4203143,0.00004464206,0.0002588554,0.006317677,0.0005942225,0.002984577,0.5590183,0.001667921,0.007829391,0.00005849957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964767,0.0009125814,0.001048953,0.0002069773,0.00004677104,0.000004697857,0.0004448992,0.00004032823,0.0008180229],"genre_scores_gemma":[0.9968682,0.0003424429,0.0003938807,0.00004424376,0.000009692204,0.000008924348,0.0002328055,0.0000349316,0.002064745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003846477,"threshold_uncertainty_score":0.01286769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007889642086042651,"score_gpt":0.2464054726094345,"score_spread":0.2385158305233918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}