{"id":"W3211123456","doi":"10.1002/chem.202103886","title":"Gold N‐Heterocyclic Carbene Catalysts for the Hydrofluorination of Alkynes Using Hydrofluoric Acid: Reaction Scope, Mechanistic Studies and the Tracking of Elusive Intermediates","year":2021,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO","funders":"Bijzonder Onderzoeksfonds UGent; Natural Sciences and Engineering Research Council of Canada; Vlaamse regering; Universiteit Gent; Fonds Wetenschappelijk Onderzoek; Fonds de recherche du Québec – Nature et technologies; Université Laval; Agentschap Innoveren en Ondernemen; King Abdullah University of Science and Technology","keywords":"Chemoselectivity; Carbene; Catalysis; Chemistry; Phosphine; Combinatorial chemistry; Reactivity (psychology); Trifluoromethanesulfonate; Counterion; Substrate (aquarium); Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006544124,0.0002190762,0.0003872115,0.00003617821,0.0002998082,0.00006640732,0.0002803084,0.00004673559,0.00001173935],"category_scores_gemma":[0.00146194,0.0001497717,0.0002137977,0.0001807555,0.0003574906,0.0001579666,0.000179055,0.0003914936,7.806399e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001610708,"about_ca_system_score_gemma":0.00008502066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001222523,"about_ca_topic_score_gemma":0.000003243054,"domain_scores_codex":[0.9985055,0.00007367582,0.0006738118,0.0002526531,0.0002763492,0.0002180547],"domain_scores_gemma":[0.9974629,0.0006812933,0.0008830536,0.0003742272,0.000529911,0.00006859647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008220514,0.00004334903,0.00002078877,0.0005301809,0.0004595789,0.00002618013,0.001007929,0.00003424048,0.9937152,0.00002109532,0.00005838483,0.004000852],"study_design_scores_gemma":[0.001668141,0.00001257114,0.00005267418,0.0005382039,0.0007097099,0.001540196,0.004888914,0.00192593,0.9880497,0.0002339981,0.0002336084,0.0001462881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829679,0.01507142,0.0006127205,0.0001891784,0.0002302843,0.0001007546,0.00003172006,0.00001814184,0.0007778736],"genre_scores_gemma":[0.9972082,0.0017911,0.0001441405,0.000009629039,0.0005065014,0.000008380557,0.00001934166,0.00004222751,0.0002704565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01424031,"threshold_uncertainty_score":0.6107511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03780081101026159,"score_gpt":0.2880142117218857,"score_spread":0.2502134007116241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}