{"id":"W3211123456","doi":"10.1002/chem.202103886","title":"Gold N‐Heterocyclic Carbene Catalysts for the Hydrofluorination of Alkynes Using Hydrofluoric Acid: Reaction Scope, Mechanistic Studies and the Tracking of Elusive Intermediates","year":2021,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO","funders":"Bijzonder Onderzoeksfonds UGent; Natural Sciences and Engineering Research Council of Canada; Vlaamse regering; Universiteit Gent; Fonds Wetenschappelijk Onderzoek; Fonds de recherche du Québec – Nature et technologies; Université Laval; Agentschap Innoveren en Ondernemen; King Abdullah University of Science and Technology","keywords":"Chemoselectivity; Carbene; Catalysis; Chemistry; Phosphine; Combinatorial chemistry; Reactivity (psychology); Trifluoromethanesulfonate; Counterion; Substrate (aquarium); Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000253215,0.0002872925,0.0002252133,0.0001038806,0.000147372,0.0002328042,0.0003611174,0.0003396152,0.0006367117],"category_scores_gemma":[0.0002080181,0.0001031852,0.0001472765,0.00009303923,0.0002565525,0.000261908,0.0002108127,0.0003407326,0.0001574726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004148886,"about_ca_system_score_gemma":0.0002528705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002006428,"about_ca_topic_score_gemma":0.005220643,"domain_scores_codex":[0.999878,0.00001130471,0.00000722308,0.00003121515,0.00004200097,0.00003016366],"domain_scores_gemma":[0.9999532,0.0000111737,0.0000119449,0.000007827742,0.000008709339,0.000007229039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001005153,0.00003479012,0.0002974036,0.0002147082,0.00001346706,0.0001195535,0.00006192341,0.0004254317,0.9897921,0.0006661341,0.0001075733,0.008166361],"study_design_scores_gemma":[0.000008413854,0.0001276494,0.0005121664,0.000005910589,0.000008118097,0.0001053072,0.00001372794,0.0008611112,0.996795,0.00004673376,0.001510979,0.000004955882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836197,0.003512754,0.007712696,0.0001142698,0.00001914563,0.00006988031,0.0001490547,0.00008667557,0.00471581],"genre_scores_gemma":[0.9941016,0.001223569,0.003578082,0.0000171546,0.000003113342,0.00001059219,0.00009176066,0.000007680755,0.0009664029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002006428,"threshold_uncertainty_score":0.003989458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03780081101026159,"score_gpt":0.2880142117218857,"score_spread":0.2502134007116241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}