{"id":"W3211156900","doi":"10.1016/j.jdermsci.2021.10.006","title":"Pathological functions of granzyme B in inflammatory skin diseases","year":2021,"lang":"en","type":"review","venue":"Journal of Dermatological Science","topic":"Autoimmune Bullous Skin Diseases","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Vancouver Coastal Health Research Institute; International Collaboration On Repair Discoveries","funders":"","keywords":"Granzyme B; Granzyme; Atopic dermatitis; Granzyme A; Immunology; Medicine; Immune system; T cell; CD8; Perforin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007534831,0.0003355321,0.003059351,0.0006740781,0.00009520245,0.00004453782,0.0009546821,0.0003012974,0.0002686813],"category_scores_gemma":[0.005219156,0.0001950681,0.00115211,0.00166658,0.001464264,0.000193537,0.0004297259,0.0008172905,0.00001883792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002229082,"about_ca_system_score_gemma":0.002683319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001148663,"about_ca_topic_score_gemma":3.58122e-7,"domain_scores_codex":[0.9957319,0.0003564042,0.001986563,0.0003797858,0.00110155,0.000443819],"domain_scores_gemma":[0.9965966,0.0005276636,0.001441367,0.0005636698,0.0004562467,0.00041443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002210429,0.006912727,0.07116262,0.02286426,0.0003619459,0.05305379,0.0001582925,0.00002850679,0.00008955108,0.002398453,0.005777488,0.8369713],"study_design_scores_gemma":[0.00177502,0.0007376574,0.1474625,0.04768769,0.002956929,0.05335462,0.0002927412,0.00001312696,0.00003201747,0.000524966,0.7443604,0.0008023814],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0109284,0.9879826,0.00003323164,0.0001357471,0.0002683741,0.0003249994,0.00002392699,0.00001740595,0.0002853377],"genre_scores_gemma":[0.02149889,0.9778332,0.0004313548,0.00008307433,0.00008050788,0.00001536139,0.00001072503,0.00001458726,0.00003236946],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8361689,"threshold_uncertainty_score":0.7954646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03745117063816236,"score_gpt":0.3511150061311739,"score_spread":0.3136638354930115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}