{"id":"W3211302556","doi":"10.3390/molecules26216478","title":"Advances in [18F]Trifluoromethylation Chemistry for PET Imaging","year":2021,"lang":"en","type":"review","venue":"Molecules","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Trifluoromethylation; Chemistry; Pet imaging; Positron emission tomography; Radiosynthesis; Radiochemistry; Combinatorial chemistry; Nanotechnology; Trifluoromethyl; Nuclear medicine; Organic chemistry; Medicine; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001431654,0.0008186256,0.0004660486,0.0008253562,0.0002618683,0.0005061947,0.0006305832,0.001308766,0.002455954],"category_scores_gemma":[0.0007738921,0.0003614439,0.0004940293,0.000693544,0.0005750073,0.001718211,0.0005870924,0.00187267,0.001381456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007509213,"about_ca_system_score_gemma":0.000550563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008658329,"about_ca_topic_score_gemma":0.0008268286,"domain_scores_codex":[0.9995382,0.00010741,0.0000320791,0.0001140479,0.0001466353,0.0000616719],"domain_scores_gemma":[0.9997334,0.0001133928,0.00005552415,0.00001902609,0.00006003318,0.00001858507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000249788,0.0001789572,0.0004911295,0.008918221,0.00008929674,0.001095049,0.0004620509,0.00355123,0.4481233,0.06492947,0.01509988,0.4568115],"study_design_scores_gemma":[0.00005206757,0.0008030029,0.0008704079,0.0005768252,0.00006941161,0.002230176,0.00005624856,0.003414691,0.2490389,0.009391037,0.7333776,0.0001196373],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02803599,0.7981925,0.1320249,0.003699768,0.001214075,0.0001712783,0.0003635829,0.0005753318,0.0357227],"genre_scores_gemma":[0.1687667,0.7518785,0.0670861,0.001729949,0.001148647,0.0003274975,0.0005592174,0.0001412966,0.008362011],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002455954,"threshold_uncertainty_score":0.008215964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09451365910640072,"score_gpt":0.4870786489467461,"score_spread":0.3925649898403454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}