{"id":"W3211313464","doi":"10.5114/aoms/143476","title":"Treatment adherence and effect of concurrent statin intensity on the efficacy and safety of alirocumab in a real-life setting: results from ODYSSEY APPRISE","year":2021,"lang":"en","type":"article","venue":"Archives of Medical Science","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université du Québec à Chicoutimi","funders":"Sanofi","keywords":"Medicine; Alirocumab; Statin; Internal medicine; Pharmacology; Total cholesterol; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001620145,0.00009483813,0.0004663055,0.00004630729,0.00004672748,0.000004267133,0.0001319631,0.0000321273,0.000008587147],"category_scores_gemma":[0.005562577,0.00005082276,0.0000596343,0.0002032048,0.001290906,0.00001943338,0.0001531654,0.0001517799,1.953404e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001777232,"about_ca_system_score_gemma":0.0005367997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002215534,"about_ca_topic_score_gemma":0.00007160097,"domain_scores_codex":[0.9979204,0.0002741816,0.0003904078,0.0003234903,0.0009240654,0.0001674826],"domain_scores_gemma":[0.9969791,0.002227254,0.0001350656,0.0003492551,0.0000393359,0.0002699462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00391894,0.0005638,0.02303339,0.000418944,0.0001253315,0.00009771266,0.01068083,0.000007499986,0.01255962,0.001257496,0.00002105172,0.9473154],"study_design_scores_gemma":[0.01189287,0.003262576,0.9343838,0.002194989,0.00008224707,0.00002501621,0.0009414633,0.003199754,0.04370775,0.0001119052,0.000107362,0.00009025707],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963367,0.0005283936,0.0000749443,0.002183646,0.0000366897,0.0004008939,0.00003519145,0.000003882983,0.0003996475],"genre_scores_gemma":[0.9974514,0.002202752,0.0002409818,0.0000630232,0.00002114502,0.000006137374,0.000007661361,0.000002746503,0.000004183797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9472251,"threshold_uncertainty_score":0.6659327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02417328369820428,"score_gpt":0.3191330901341385,"score_spread":0.2949598064359343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}