{"id":"W3211524163","doi":"10.1093/neuonc/noab196.080","title":"STEM-04. PD-1 INDEPENDENT OF PD-L1 LIGATION PROMOTES GLIOBLASTOMA GROWTH THROUGH THE NFkB PATHWAY","year":2021,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Glioblastoma; Cancer research; PD-L1; Immune system; Stem cell; Biology; Cell biology; Immunology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000127094,0.0001556648,0.0002148795,0.00002747442,0.0001005535,0.00002042927,0.0002281832,0.0001884454,0.00005118581],"category_scores_gemma":[0.0001620979,0.0001184215,0.0001219387,0.0001673901,0.0001507226,0.000008044834,0.0002574212,0.0001866375,0.00001999913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006425462,"about_ca_system_score_gemma":0.0006033597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001194702,"about_ca_topic_score_gemma":0.000720352,"domain_scores_codex":[0.9984721,0.0003037732,0.0002546721,0.0004136349,0.0002449181,0.0003109158],"domain_scores_gemma":[0.999043,0.0001007708,0.0001415018,0.0004054826,0.0002309856,0.00007818794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003773052,0.0003394286,0.001506482,0.00003129871,0.0001150466,0.0001477436,0.0002381382,0.000007853359,0.9859045,0.0003107255,0.001712221,0.009309307],"study_design_scores_gemma":[0.001095397,0.002287737,0.0009431671,0.00000874832,0.00002304233,0.0001531956,0.0001652414,0.000008626739,0.9311801,0.0003839288,0.06365684,0.00009396204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927363,0.001002134,0.000115558,0.00178076,0.0002745549,0.0003809628,0.00005684506,0.00001329809,0.003639524],"genre_scores_gemma":[0.9982596,0.0004618979,0.00008427929,0.0005696914,0.000189796,0.0000954263,0.0000661115,0.00002303886,0.0002501657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06194462,"threshold_uncertainty_score":0.482909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01781282325304446,"score_gpt":0.2927611497394863,"score_spread":0.2749483264864419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}