{"id":"W3211587765","doi":"10.1097/mcg.0000000000001636","title":"Week 2 Adalimumab Levels Predict Short-term Clinical Remission in Patients With Inflammatory Bowel Disease","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Adalimumab; Medicine; Odds ratio; Confidence interval; Internal medicine; Receiver operating characteristic; Gastroenterology; Inflammatory bowel disease; Area under the curve; Retrospective cohort study; Logistic regression; Surgery; Tumor necrosis factor alpha; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001685197,0.0002709741,0.0006497066,0.00008692357,0.00004182384,0.00002269945,0.0004022272,0.0003304677,0.00007020921],"category_scores_gemma":[0.001691747,0.0002208896,0.0005381783,0.00005098841,0.0003223681,0.00002518906,0.0002533582,0.0007614259,0.000005852841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003054307,"about_ca_system_score_gemma":0.0007872066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":1.812942e-7,"about_ca_topic_score_gemma":0.00002841939,"domain_scores_codex":[0.9946728,0.001316996,0.002590125,0.0005174375,0.0004335165,0.0004690823],"domain_scores_gemma":[0.9970369,0.0001041739,0.0008276872,0.0005813339,0.0006076505,0.0008422257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02362222,0.00165465,0.9700205,0.00003798288,0.0002039566,0.002075861,0.000006905059,0.0001139766,0.0001331502,0.000002693419,0.001214884,0.0009131603],"study_design_scores_gemma":[0.009212018,0.003021768,0.9861214,0.000143368,0.0001195245,0.00004046481,0.00001300397,0.00003960443,0.00002745057,0.00002408494,0.001095885,0.0001414139],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981576,0.00007254384,0.0003278406,0.0002846071,0.0008890976,0.000179157,0.00004092896,0.000006835964,0.00004139238],"genre_scores_gemma":[0.997034,0.000120104,0.0005470944,0.001186188,0.0009347968,0.000004981349,0.00006320732,0.00003921461,0.0000704475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01610086,"threshold_uncertainty_score":0.9007617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02323994090422105,"score_gpt":0.3168915234688022,"score_spread":0.2936515825645812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}