{"id":"W3211591471","doi":"10.3389/fcell.2021.743908","title":"Clinical Impact of Molecular Subtyping of Pancreatic Cancer","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Pancreatic cancer; KRAS; Biology; Cancer research; Malignancy; Cancer; Adenocarcinoma; Transcriptome; Targeted therapy; Gene; Colorectal cancer; Genetics; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004842763,0.0002345259,0.003685154,0.0002671815,0.00001561101,0.00000170287,0.0001037396,0.0005373936,0.0001509341],"category_scores_gemma":[0.000153601,0.0001643041,0.0003735818,0.0002728836,0.0004102566,0.00001085946,0.0001275911,0.0003757028,0.000002020715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002164186,"about_ca_system_score_gemma":0.002549043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000218587,"about_ca_topic_score_gemma":0.000005053303,"domain_scores_codex":[0.9979309,0.0003358699,0.00102012,0.0003493651,0.00008557116,0.0002781468],"domain_scores_gemma":[0.9991019,0.0002745117,0.0002978589,0.0001472407,0.00006091912,0.0001176099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005727665,0.0001359778,0.5522212,0.006218994,0.000856376,0.00005848276,0.00005107952,3.184715e-8,0.00003342175,0.000006801863,0.0008615553,0.4394988],"study_design_scores_gemma":[0.0153508,0.006226021,0.1314926,0.1080559,0.01307284,0.0009633745,0.001814938,0.0001194866,0.0007093851,0.0006516551,0.7188194,0.002723587],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04609449,0.9514058,0.0001118141,0.000005089267,0.0001915866,0.0004535996,0.00004510048,0.000003381916,0.001689144],"genre_scores_gemma":[0.001560258,0.984713,0.01320013,0.00001669858,0.00002623848,0.000047416,0.0001865826,0.0000166508,0.0002330619],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7179579,"threshold_uncertainty_score":0.6700126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06620116796063016,"score_gpt":0.4379246674998459,"score_spread":0.3717234995392158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}