{"id":"W3211591471","doi":"10.3389/fcell.2021.743908","title":"Clinical Impact of Molecular Subtyping of Pancreatic Cancer","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Pancreatic cancer; KRAS; Biology; Cancer research; Malignancy; Cancer; Adenocarcinoma; Transcriptome; Targeted therapy; Gene; Colorectal cancer; Genetics; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001480244,0.0005641408,0.0008944425,0.001391892,0.0003415177,0.001114654,0.0005004515,0.0003406824,0.002278674],"category_scores_gemma":[0.005524261,0.0001484074,0.0004476148,0.001257808,0.0003568949,0.0009140317,0.000616921,0.0009418264,0.0009203811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006056473,"about_ca_system_score_gemma":0.0004464077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001369757,"about_ca_topic_score_gemma":0.002044583,"domain_scores_codex":[0.9991372,0.0002457243,0.0001034006,0.0001956702,0.0002420922,0.00007582759],"domain_scores_gemma":[0.9967875,0.001141461,0.0005590012,0.0003502537,0.0006694447,0.0004923841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002462817,0.00016707,0.5891146,0.0003723304,0.0001723293,0.001098995,0.00008562137,0.001181244,0.01505273,0.0003852418,0.004444966,0.3854621],"study_design_scores_gemma":[0.00009385826,0.001636475,0.9413456,0.0002519135,0.0005763017,0.008353195,0.0003913266,0.003822167,0.01015346,0.002819088,0.03049162,0.00006511933],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8670293,0.08488314,0.005733446,0.006291682,0.001361451,0.0002178751,0.001964487,0.0003721346,0.03214663],"genre_scores_gemma":[0.9797595,0.01000279,0.004285627,0.001082539,0.0007990354,0.00005046053,0.001956118,0.00008806022,0.001975801],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002278674,"threshold_uncertainty_score":0.007828355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06620116796063016,"score_gpt":0.4379246674998459,"score_spread":0.3717234995392158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}