{"id":"W3211600372","doi":"10.1002/jcb.30173","title":"Review of cancer cell resistance mechanisms to apoptosis and actual targeted therapies","year":2021,"lang":"en","type":"review","venue":"Journal of Cellular Biochemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Apoptosis; Cancer research; Mechanism (biology); Cancer; Medicine; Biology; Internal medicine; Genetics; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003454792,0.0008240871,0.001162973,0.00249465,0.0002789515,0.0008500557,0.0008916678,0.0007757919,0.005451793],"category_scores_gemma":[0.0005370859,0.0002709448,0.0004292025,0.002970356,0.0002921589,0.001232917,0.0005615095,0.001386777,0.003285199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005971481,"about_ca_system_score_gemma":0.0009009585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007182231,"about_ca_topic_score_gemma":0.001221372,"domain_scores_codex":[0.9998364,0.00002473839,0.00002459766,0.00002841257,0.0000694919,0.00001639339],"domain_scores_gemma":[0.9997736,0.0000787855,0.00003303115,0.000008274933,0.00007770753,0.00002861805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001033731,0.0000984353,0.0001141763,0.02538281,0.00008786978,0.0002996771,0.00007175259,0.0004586288,0.003356197,0.003862822,0.1100556,0.8561087],"study_design_scores_gemma":[0.00000955349,0.00007146371,0.0004452259,0.002344368,0.00007405179,0.001091317,0.00002751779,0.00005527509,0.0003578552,0.001144846,0.9943657,0.00001287437],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001271254,0.997404,0.0001649678,0.0002299311,0.0005437158,0.000006727306,0.00003518771,0.00001236812,0.001475885],"genre_scores_gemma":[0.0004454982,0.9976863,0.0001933788,0.0002139576,0.0003106344,0.000006921398,0.00005363073,0.000002054159,0.001087652],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005451793,"threshold_uncertainty_score":0.01823807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01214676014502876,"score_gpt":0.2850731324883608,"score_spread":0.2729263723433321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}