{"id":"W3211628450","doi":"10.1165/rcmb.2020-0504oc","title":"Connective-Tissue Growth Factor Contributes to TGF-β1–induced Lung Fibrosis","year":2021,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research","keywords":"CTGF; Downregulation and upregulation; Extracellular matrix; Fibrosis; Growth factor; Pulmonary fibrosis; Idiopathic pulmonary fibrosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002049422,0.0005106854,0.0002094101,0.0004111443,0.0001826318,0.0002448813,0.0001306641,0.000273343,0.001422825],"category_scores_gemma":[0.0001508332,0.0001038372,0.0002960847,0.0001431554,0.0002946788,0.0001537851,0.0001976149,0.0006486573,0.0002857145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002130624,"about_ca_system_score_gemma":0.0002156688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005286824,"about_ca_topic_score_gemma":0.0005294265,"domain_scores_codex":[0.9998679,0.00003748753,0.00000898203,0.00001644097,0.00003301814,0.00003618954],"domain_scores_gemma":[0.9998369,0.0000242366,0.00004987714,0.00001339546,0.00001715091,0.00005840055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002437906,0.00006830053,0.001221464,0.0001031511,0.00000790688,0.000470181,0.00002515887,0.000054786,0.994979,0.0001401158,0.00005693035,0.002629218],"study_design_scores_gemma":[0.0001440144,0.00111057,0.05903586,0.00006441596,0.0001139684,0.004474831,0.000138775,0.003131834,0.9213076,0.0005093033,0.009954976,0.00001385781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841371,0.009289955,0.002985638,0.0003011519,0.00007240982,0.00006701637,0.0001449577,0.00008847746,0.002913318],"genre_scores_gemma":[0.9930184,0.003648253,0.001174207,0.00007616494,0.00005517689,0.00002960981,0.0001725601,0.000009049207,0.00181656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001422825,"threshold_uncertainty_score":0.004759789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01144516328570897,"score_gpt":0.303525161022214,"score_spread":0.292079997736505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}