{"id":"W3211648737","doi":"10.4049/jimmunol.2100025","title":"CD24 and IgM Stimulation of B Cells Triggers Transfer of Functional B Cell Receptor to B Cell Recipients Via Extracellular Vesicles","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; University of British Columbia; Memorial University of Newfoundland","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Beatrice Hunter Cancer Research Institute","keywords":"Cell biology; CD24; Flow cytometry; Chemistry; B cell; Microvesicle; Cell; Receptor; CD40; B-cell receptor; Extracellular vesicle; Stimulation; Biology; Immunology; Molecular biology; Microvesicles; Stem cell; Cytotoxic T cell; In vitro; Antibody; Biochemistry; microRNA; Endocrinology; Cancer stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000498973,0.0001381189,0.0002602799,0.00008087411,0.00004769113,0.000005406559,0.0002211148,0.0001501064,0.0001192598],"category_scores_gemma":[0.00005857267,0.0001138826,0.0001438987,0.0001311217,0.0001764746,0.000009632686,0.00007618178,0.0001656889,0.000005009491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001699259,"about_ca_system_score_gemma":0.0001317669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004297096,"about_ca_topic_score_gemma":0.000001407452,"domain_scores_codex":[0.9985777,0.0003192282,0.0005914425,0.0001534506,0.0001881112,0.0001700359],"domain_scores_gemma":[0.9989125,0.00008628365,0.0002722244,0.000306755,0.0003490112,0.00007319792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001256894,0.000286117,0.0003388334,0.00003604202,0.0001110629,0.000005293443,0.0002208758,0.001540015,0.9942731,0.00001231029,0.0003759846,0.001543452],"study_design_scores_gemma":[0.001258843,0.000693775,0.002435066,0.00002592315,0.000120175,0.00004323227,0.0002341683,0.00003279181,0.9932153,0.00008049735,0.001756298,0.000103912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701365,0.01468023,0.01447736,0.0001279679,0.0003604352,0.0001137719,0.00001919963,0.000001777053,0.00008273766],"genre_scores_gemma":[0.997203,0.001025302,0.001179706,0.00004579874,0.00008186597,0.000001250826,0.00001725034,0.00002003776,0.0004257936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02706647,"threshold_uncertainty_score":0.4643999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008129354448753566,"score_gpt":0.2133969038996205,"score_spread":0.2052675494508669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}