{"id":"W3211648737","doi":"10.4049/jimmunol.2100025","title":"CD24 and IgM Stimulation of B Cells Triggers Transfer of Functional B Cell Receptor to B Cell Recipients Via Extracellular Vesicles","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; University of British Columbia; Memorial University of Newfoundland","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Beatrice Hunter Cancer Research Institute","keywords":"Cell biology; CD24; Flow cytometry; Chemistry; B cell; Microvesicle; Cell; Receptor; CD40; B-cell receptor; Extracellular vesicle; Stimulation; Biology; Immunology; Molecular biology; Microvesicles; Stem cell; Cytotoxic T cell; In vitro; Antibody; Biochemistry; microRNA; Endocrinology; Cancer stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002129858,0.0004954781,0.0003101288,0.0002259429,0.0001354088,0.0004544571,0.0002311487,0.0005595661,0.002231388],"category_scores_gemma":[0.0001355293,0.0001753373,0.0004643383,0.0001477147,0.0001380409,0.0002480929,0.0004952005,0.0008247843,0.000760092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002055303,"about_ca_system_score_gemma":0.0001026185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001275566,"about_ca_topic_score_gemma":0.0001316929,"domain_scores_codex":[0.9995602,0.0001086008,0.00002717141,0.00007624729,0.0000802888,0.0001474338],"domain_scores_gemma":[0.9999013,0.00002203429,0.00002348388,0.00001499878,0.000007591927,0.00003054562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000117645,0.00003715545,0.00008169886,0.00003193048,0.00000535655,0.00007056692,0.00001510143,0.00003935255,0.998709,0.0001190099,0.00002878081,0.0007444344],"study_design_scores_gemma":[0.00002871725,0.0004331282,0.001800566,0.000007909379,0.00001502506,0.0002900437,0.00002847663,0.0005632869,0.9942081,0.00006322849,0.002556747,0.000004731359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933777,0.001596336,0.002104189,0.00006969064,0.00004947804,0.00004964706,0.0001927451,0.00007853888,0.002481614],"genre_scores_gemma":[0.9949451,0.0006163562,0.001705173,0.00006738146,0.00002006277,0.00006964234,0.0002516967,0.00002398846,0.002300626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002231388,"threshold_uncertainty_score":0.007464767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008129354448753566,"score_gpt":0.2133969038996205,"score_spread":0.2052675494508669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}