{"id":"W3211662792","doi":"10.32920/ryerson.14652993.v1","title":"Simulation of Enzymatic Production of Amoxicillin","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Yield (engineering); Substrate (aquarium); Chemistry; Amoxicillin; Agarose; Commercialization; Enzyme; Chromatography; Organic chemistry; Materials science; Biochemistry; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001508463,0.0001039256,0.0002143602,0.00004677947,0.000008147652,0.000005403946,0.00008473112,0.000207335,0.00002565094],"category_scores_gemma":[0.0003457994,0.00009900673,0.0001182419,0.00007829236,0.000036673,0.0000014385,0.0001649947,0.00005622184,2.390819e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007018098,"about_ca_system_score_gemma":0.00008095934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001803442,"about_ca_topic_score_gemma":0.00001890059,"domain_scores_codex":[0.9991229,0.00004812891,0.0003736384,0.0002794137,0.0001181925,0.00005773606],"domain_scores_gemma":[0.9987748,0.000008400486,0.0003087842,0.0004806142,0.0004128335,0.00001459215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008880491,0.00006758759,0.0003256792,0.0002949781,0.00005560657,4.186845e-8,0.00004623043,0.3415624,0.6573018,0.00000758898,0.00003996155,0.0002892969],"study_design_scores_gemma":[0.00006817908,0.00004765123,0.0003864474,0.00008178128,0.00005058233,2.765548e-7,0.00008872346,0.01425091,0.9848096,0.00002695077,0.00009616274,0.00009268171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818071,0.0007838677,0.01659269,0.00001519192,0.0002349676,0.0001925221,0.000004637218,0.000004234961,0.0003647944],"genre_scores_gemma":[0.9970047,0.0001602812,0.0009145782,0.00000844537,0.00009178784,0.000009772306,0.001135244,0.00001210105,0.0006631073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3275079,"threshold_uncertainty_score":0.4037377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01607103591293631,"score_gpt":0.2707756440121838,"score_spread":0.2547046080992475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}