{"id":"W3211811917","doi":"10.1055/a-1696-5713","title":"Asymmetric Rhodium-Catalyzed Allylic Substitution Reactions with Nitrile-Stabilized Carbanions","year":2021,"lang":"en","type":"article","venue":"Synlett","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Queen's University; Canada Research Chairs; Government of Ontario","keywords":"Chemistry; Nitrile; Carbanion; Enantioselective synthesis; Allylic rearrangement; Stereocenter; Rhodium; Tsuji–Trost reaction; Alkylation; Nucleophile; Substitution reaction; Catalysis; Combinatorial chemistry; Organic chemistry; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001886472,0.0002460779,0.0003266777,0.000353211,0.0003013996,0.00008024568,0.0002139636,0.0001760888,0.00232759],"category_scores_gemma":[0.000632163,0.0002294625,0.0002026522,0.003311488,0.0001001139,0.0002019157,0.00006350995,0.000313787,0.0003377002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002526964,"about_ca_system_score_gemma":0.0003361054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001534442,"about_ca_topic_score_gemma":0.00008864639,"domain_scores_codex":[0.9980963,0.00005346551,0.0004041382,0.0005374053,0.000536277,0.0003724224],"domain_scores_gemma":[0.9982609,0.0002255019,0.0001770157,0.0007777907,0.0003466056,0.0002121654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002998581,0.002425224,0.01589367,0.0005712445,0.002325521,0.0008271699,0.0006410409,0.0008012902,0.9093533,0.02585518,0.007637388,0.03336915],"study_design_scores_gemma":[0.00285631,0.00001930261,0.001038146,0.00006681636,0.0005583982,0.0003621103,0.0007691282,0.0009021084,0.6659392,0.0001837743,0.3264803,0.0008243958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7281079,0.002230451,0.008368838,0.001518088,0.0002959013,0.0002174132,0.0001934212,0.0007451925,0.2583227],"genre_scores_gemma":[0.9914756,0.0001287354,0.0007695562,0.0001245733,0.0001565919,0.00007325023,0.0009261877,0.0000399252,0.006305546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3188429,"threshold_uncertainty_score":0.9985844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01156433495761197,"score_gpt":0.2284831867149539,"score_spread":0.2169188517573419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}