{"id":"W3211847376","doi":"10.1002/path.5833","title":"Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth","year":2021,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; British Heart Foundation; Cancer Research UK; Barts Charity","keywords":"Focal adhesion; Doxorubicin; Cancer research; Kinase; Cell growth; Medicine; Biology; Pathology; Signal transduction; Cell biology; Chemotherapy; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006461258,0.00008075792,0.0001711908,0.00002178058,0.00005356063,0.00000339767,0.0001984347,0.00006252947,0.000007329365],"category_scores_gemma":[0.0001191613,0.00004155827,0.000121495,0.00007839478,0.0001358578,0.000003862972,0.0001581518,0.0001399806,1.269059e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007292225,"about_ca_system_score_gemma":0.000090922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002776909,"about_ca_topic_score_gemma":0.00003638013,"domain_scores_codex":[0.9990324,0.0004004802,0.000254865,0.00008845998,0.0001037898,0.0001200416],"domain_scores_gemma":[0.9992776,0.00008448585,0.0003418425,0.000147157,0.0001275544,0.00002135999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001603909,0.00006354682,0.005740826,0.00001402531,0.0000139032,0.0000180949,0.0001661724,0.0001174893,0.9920275,0.00003231104,0.00001416095,0.00163161],"study_design_scores_gemma":[0.0003868047,0.0002216761,0.01070403,0.00003020253,0.00004416804,0.0002404203,0.0003978813,0.00005899164,0.9875222,0.0002343112,0.0001159222,0.00004338614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948182,0.004246797,0.0004447806,0.0002657499,0.00007312644,0.0000504746,0.00001105769,4.631578e-7,0.00008935865],"genre_scores_gemma":[0.9988568,0.0007485358,0.000143147,0.00007376696,0.0001469783,0.000001073452,7.069308e-7,0.000008249031,0.00002071636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004963203,"threshold_uncertainty_score":0.1694697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008654762831589292,"score_gpt":0.2349616197541848,"score_spread":0.2263068569225956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}