{"id":"W3211906514","doi":"10.3390/jcm10215196","title":"IRF3 Knockout Results in Partial or Complete Rejection of Murine Mesothelioma","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Medicine","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Toronto General Hospital; University of Toronto; University Health Network","funders":"Princess Margaret Hospital Foundation; Brown University","keywords":"Medicine; Mesothelioma; Knockout mouse; Cancer research; Immunology; Pathology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002515053,0.000578046,0.0003350315,0.000584128,0.0002875208,0.0003716934,0.0002975831,0.0006704818,0.003409349],"category_scores_gemma":[0.0001855593,0.0003306797,0.0008242819,0.0002016811,0.000459298,0.0003064435,0.0003315981,0.001270097,0.001093781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003524583,"about_ca_system_score_gemma":0.0002675731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005907352,"about_ca_topic_score_gemma":0.0008795836,"domain_scores_codex":[0.9995909,0.00003969626,0.00005036593,0.00009413078,0.0001011518,0.000123717],"domain_scores_gemma":[0.9995123,0.0000401821,0.0001735833,0.00006344578,0.00002459796,0.0001859067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003793981,0.00005797359,0.0005113942,0.0000619544,0.00001777766,0.0001519994,0.00002534384,0.0001241804,0.997393,0.0001207325,0.0001678507,0.0009882462],"study_design_scores_gemma":[0.0000976134,0.001014915,0.01959426,0.00004140131,0.00008008788,0.001413286,0.0001671885,0.002111407,0.9697782,0.0001912779,0.005490136,0.00002013886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904377,0.0009726586,0.002908334,0.0002225717,0.00008673222,0.00005409565,0.003447694,0.0004336661,0.001436587],"genre_scores_gemma":[0.9924173,0.0004110373,0.001696595,0.0001089633,0.0000132669,0.00007563849,0.001872893,0.00009503691,0.003309212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003409349,"threshold_uncertainty_score":0.01140541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1178742093484406,"score_gpt":0.4239969067071445,"score_spread":0.3061226973587039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}