{"id":"W3211920271","doi":"10.1073/pnas.2104721118","title":"Preferential and persistent impact of acute HIV-1 infection on CD4 <sup>+</sup> iNKT cells in colonic mucosa","year":2021,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; U.S. Department of Defense; Gilead Sciences; ViiV Healthcare; Henry M. Jackson Foundation; Office of Defense Programs; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Immunology; In vitro; Biology; Natural killer T cell; Intestinal mucosa; Viral load; Peripheral blood mononuclear cell; Immune system; Human immunodeficiency virus (HIV); T cell; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001189477,0.0001563339,0.0002672542,0.0002844705,0.000264897,0.0005807249,0.0001054562,0.0002215655,0.001660863],"category_scores_gemma":[0.0002390317,0.000140163,0.0001211299,0.000142648,0.0003184234,0.0002668911,0.0002764812,0.0007769834,0.0003378891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002555906,"about_ca_system_score_gemma":0.0001822833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003952936,"about_ca_topic_score_gemma":0.0004944684,"domain_scores_codex":[0.9998574,0.00001923198,0.00001289835,0.00003097815,0.00002098096,0.00005849723],"domain_scores_gemma":[0.9997442,0.00004103235,0.00005180395,0.00003974592,0.00002776862,0.00009534295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001044077,0.00005791425,0.009996642,0.00007936454,0.000006872094,0.000315998,0.00006092796,0.00006177057,0.9828228,0.00005681429,0.00007019597,0.005426583],"study_design_scores_gemma":[0.00004662991,0.001882504,0.308946,0.00004657551,0.00004584922,0.003708118,0.0006576445,0.001459294,0.6805713,0.0002643233,0.002351973,0.00001976456],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977054,0.0009160467,0.0003464709,0.00005099435,0.00001242756,0.000007435398,0.0001489588,0.00003331488,0.0007789966],"genre_scores_gemma":[0.9986336,0.0002317251,0.0002981178,0.00003282257,0.000009064517,0.000008910752,0.0001329072,0.000007391205,0.0006455112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001660863,"threshold_uncertainty_score":0.005556107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02498226608784249,"score_gpt":0.2844574863554983,"score_spread":0.2594752202676558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}