{"id":"W3211951539","doi":"10.1111/1759-7714.14230","title":"Circulating tumor <scp>DNA</scp> predicts the outcome of chemotherapy in patients with lung cancer","year":2021,"lang":"en","type":"article","venue":"Thoracic Cancer","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Medicine; Lung cancer; Chemotherapy; Biomarker; Oncology; Internal medicine; Cancer; Cytokeratin; Liquid biopsy; Circulating tumor DNA; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001155865,0.0001561027,0.0002116623,0.00002624158,0.00004929244,0.00002084037,0.00015686,0.00006764915,0.00004073388],"category_scores_gemma":[0.00009713174,0.0001200728,0.00006354362,0.0002000343,0.00007094079,0.000004364262,0.00008225553,0.0001087437,5.53883e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007611741,"about_ca_system_score_gemma":0.0002987068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000419556,"about_ca_topic_score_gemma":0.001358753,"domain_scores_codex":[0.9989499,0.00003642983,0.0002677049,0.000304544,0.0001845399,0.0002568346],"domain_scores_gemma":[0.999192,0.00004503415,0.0001690076,0.0003596492,0.000181157,0.00005314865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007416119,0.0000931528,0.9746666,0.00009722284,0.0001022263,0.000006809623,0.0002869684,0.002331576,0.01663693,0.0000207725,0.0008617942,0.004821779],"study_design_scores_gemma":[0.001992783,0.0001292649,0.8403031,0.000204638,0.00009412392,0.000004308874,0.0001945471,0.0004343137,0.1461615,0.00003211803,0.01026563,0.0001836074],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994476,0.004151862,0.0001067619,0.0001674279,0.0002144506,0.0002641031,0.0001521899,0.000005750542,0.0004614072],"genre_scores_gemma":[0.9978121,0.0005502786,0.0001202783,0.0008673695,0.0002167525,0.00009386894,0.00005241393,0.00003587693,0.000251076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1343635,"threshold_uncertainty_score":0.4896427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008892205310853333,"score_gpt":0.2857952267332052,"score_spread":0.2769030214223519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}