{"id":"W3211951539","doi":"10.1111/1759-7714.14230","title":"Circulating tumor <scp>DNA</scp> predicts the outcome of chemotherapy in patients with lung cancer","year":2021,"lang":"en","type":"article","venue":"Thoracic Cancer","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Medicine; Lung cancer; Chemotherapy; Biomarker; Oncology; Internal medicine; Cancer; Cytokeratin; Liquid biopsy; Circulating tumor DNA; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002514822,0.0001843297,0.0002367752,0.000409473,0.0001850231,0.0003557305,0.000133139,0.0003115504,0.0008219849],"category_scores_gemma":[0.001304843,0.00007251014,0.000127623,0.0004051462,0.0001750081,0.0002101388,0.0001690227,0.0003553844,0.0001558661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002330023,"about_ca_system_score_gemma":0.0001885753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009031554,"about_ca_topic_score_gemma":0.0009830513,"domain_scores_codex":[0.9998573,0.00002941658,0.00001737093,0.00003938243,0.0000319205,0.00002452467],"domain_scores_gemma":[0.9992424,0.0002159934,0.0002839472,0.00003310951,0.00009232724,0.0001322516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001629389,0.00001646978,0.9960169,0.00000851452,0.00001504219,0.00004752634,0.0000132273,0.00008558756,0.001218472,0.000006861271,0.00005821783,0.002350349],"study_design_scores_gemma":[0.00001057207,0.0001742338,0.9970953,0.000005978048,0.00003664276,0.0004896304,0.0000425715,0.0007814912,0.001034458,0.0000553561,0.0002709716,0.000002804758],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985749,0.0005394936,0.0002402005,0.00006097845,0.000006189606,0.000005473776,0.0001912383,0.000008082382,0.0003735928],"genre_scores_gemma":[0.9995159,0.00006561895,0.0001196956,0.00001640219,0.000007829513,0.000003841461,0.0002015978,0.000001248296,0.00006778766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009031554,"threshold_uncertainty_score":0.002749801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008892205310853333,"score_gpt":0.2857952267332052,"score_spread":0.2769030214223519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}