{"id":"W3211988828","doi":"10.1038/s41416-021-01616-2","title":"CSNK2 in cancer: pathophysiology and translational applications","year":2021,"lang":"en","type":"review","venue":"British Journal of Cancer","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; American Society of Clinical Oncology","keywords":"Cancer; Cancer research; Metastasis; Protein kinase B; Kinase; PTEN; Biology; Medicine; Cancer cell; Translational research; Cell cycle; PI3K/AKT/mTOR pathway; Bioinformatics; Signal transduction; Pathology; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001685662,0.0002064694,0.001654612,0.0002126849,0.00003935431,0.00002714902,0.0001062151,0.0003127216,0.0003478169],"category_scores_gemma":[0.00003148605,0.0002259623,0.0004272732,0.0004084767,0.00008550898,0.00005374434,0.0000230356,0.0009982852,0.000001622178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002376444,"about_ca_system_score_gemma":0.002657115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002809518,"about_ca_topic_score_gemma":0.0008539004,"domain_scores_codex":[0.9982612,0.0001139109,0.0008685968,0.0002746155,0.0002721731,0.0002094994],"domain_scores_gemma":[0.998858,0.00006742614,0.0005256943,0.0001284049,0.0002669949,0.0001534693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001264384,0.00006370186,0.00002170338,0.003163079,0.0002611003,0.0006977364,0.0000177724,0.00001623199,0.00001932387,0.00002397832,0.0007309133,0.9949718],"study_design_scores_gemma":[0.0009400878,0.00004546234,0.0002571762,0.04309927,0.001078053,0.005100023,0.000006271298,0.000002838421,0.000002926946,0.00006576247,0.9492282,0.0001739009],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000665663,0.9983621,0.000156259,0.0001955045,0.0003013683,0.0005285363,0.0002486912,0.000005945586,0.0001350174],"genre_scores_gemma":[0.00003077776,0.9981511,0.0003395875,0.0001730439,0.0008137402,0.0002735315,0.00005912488,0.00005168239,0.0001074204],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9947979,"threshold_uncertainty_score":0.9214475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02864454249435183,"score_gpt":0.3613751296212475,"score_spread":0.3327305871268957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}