{"id":"W3212033307","doi":"10.25251/skin.5.supp.57","title":"Assessing long-term maintenance of efficacy with tralokinumab monotherapy in patients with moderate-to-severe atopic dermatitis: combined results from two phase 3, randomized, double-blind, placebo-controlled trials (ECZTRA 1 and 2)","year":2021,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"LEO Pharma","keywords":"Atopic dermatitis; Medicine; Placebo; Double blind; Term (time); Randomized controlled trial; Placebo-controlled study; Dermatology; Pediatrics; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005365945,0.001924228,0.00559538,0.0006194796,0.0006535355,0.001517171,0.00115455,0.002388005,0.003240839],"category_scores_gemma":[0.002722917,0.000744991,0.00527503,0.0006372408,0.001087074,0.001929899,0.0005079284,0.003232388,0.0006147856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009045131,"about_ca_system_score_gemma":0.001128212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001035025,"about_ca_topic_score_gemma":0.002777686,"domain_scores_codex":[0.9983044,0.0008524774,0.0001984498,0.0002703293,0.0001596077,0.0002147107],"domain_scores_gemma":[0.9976134,0.0008257512,0.0006523091,0.0002250037,0.0001972977,0.0004861828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9606218,0.003658927,0.001573943,0.001221627,0.005216147,0.00003942451,0.00007898452,0.0002759267,0.004309471,0.00003281931,0.0004197072,0.02255131],"study_design_scores_gemma":[0.8881598,0.09764438,0.008926261,0.00007817035,0.003570375,0.00007080431,0.00003832465,0.0002373792,0.0006525061,0.00006762629,0.0005219521,0.00003239343],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9666585,0.02740896,0.0007568948,0.0006107251,0.0004376809,0.001605261,0.001092769,0.0001222922,0.001306964],"genre_scores_gemma":[0.9859326,0.007454629,0.001382746,0.000833114,0.000472613,0.001578352,0.001342294,0.00002419348,0.000979373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00559538,"threshold_uncertainty_score":0.02837813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02369982572407136,"score_gpt":0.3222182094772743,"score_spread":0.2985183837532029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}