{"id":"W3212214778","doi":"10.1158/1538-7445.panca21-ia-003","title":"Abstract IA-003: Proteogenomic characterizations of pancreatic ductal adenocarcinoma","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Pancreatic cancer; Cancer research; Biology; Epigenomics; Cancer; Carcinogenesis; Proteogenomics; Adenocarcinoma; Tumor microenvironment; Computational biology; DNA methylation; Genomics; Gene; Genome; Genetics; Gene expression; Tumor cells","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002775611,0.0004213752,0.0003200358,0.00116785,0.0003239571,0.0005841645,0.0002297064,0.0003371043,0.001416448],"category_scores_gemma":[0.0003169768,0.0001373531,0.000391818,0.001233267,0.00015567,0.0001960471,0.0003774679,0.0003389655,0.0005900462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001984156,"about_ca_system_score_gemma":0.0002847508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001141248,"about_ca_topic_score_gemma":0.001077617,"domain_scores_codex":[0.9998467,0.00001638907,0.00001615156,0.00004561659,0.00005061166,0.00002444014],"domain_scores_gemma":[0.999864,0.00001763105,0.0000268747,0.00001721506,0.00005038022,0.00002392582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002383258,0.00003685101,0.007939475,0.0001494752,0.00005181415,0.0002106337,0.00004833535,0.0004675524,0.9818863,0.000105738,0.0009399647,0.007925581],"study_design_scores_gemma":[0.00002614093,0.0003336979,0.3937428,0.00003949998,0.0002254047,0.002940273,0.0003138843,0.01149341,0.5661454,0.0004474153,0.0242249,0.00006730628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9528517,0.002015803,0.0119689,0.0002675648,0.00009620481,0.0001296188,0.02905951,0.0005232399,0.003087489],"genre_scores_gemma":[0.9100501,0.002506256,0.02978388,0.0002808358,0.00006588097,0.0002197547,0.05130314,0.0002599346,0.005530326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001416448,"threshold_uncertainty_score":0.00473845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1148256809657899,"score_gpt":0.4461626039202047,"score_spread":0.3313369229544147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}