{"id":"W3212256991","doi":"10.1182/blood-2018-99-117045","title":"Two-Year Follow-up of Keynote-087 Study: Pembrolizumab Monotherapy in Relapsed/Refractory Classic Hodgkin Lymphoma","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Pembrolizumab; Medicine; Brentuximab vedotin; Internal medicine; Oncology; Cohort; Population; Salvage therapy; Refractory (planetary science); Clinical endpoint; Autologous stem-cell transplantation; Chemotherapy regimen; Transplantation; Surgery; Lymphoma; Chemotherapy; Clinical trial; Cancer; Hodgkin lymphoma; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002589714,0.0006149104,0.001325429,0.0003810506,0.0006672331,0.0009217792,0.0005120978,0.001072463,0.002616432],"category_scores_gemma":[0.001619846,0.0003161483,0.001022379,0.0003629326,0.0003247874,0.0009986479,0.0005809092,0.001815243,0.0006635373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007820197,"about_ca_system_score_gemma":0.0006205855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009221929,"about_ca_topic_score_gemma":0.001302999,"domain_scores_codex":[0.9990846,0.000261995,0.00007841888,0.0002490671,0.0001345267,0.0001913501],"domain_scores_gemma":[0.998553,0.0002186113,0.0003526279,0.0002363199,0.0002535195,0.0003859353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3968537,0.01288703,0.4250076,0.0008494501,0.007023111,0.001566286,0.0006986087,0.002966114,0.02999241,0.0004718375,0.01191474,0.1097692],"study_design_scores_gemma":[0.0301738,0.178368,0.7650462,0.0001225207,0.004751718,0.001492666,0.0002772177,0.002148104,0.005758848,0.0003200886,0.01145851,0.00008221361],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914182,0.001710281,0.0004190914,0.0001754456,0.00006004578,0.0004684023,0.003141803,0.00004694441,0.00255968],"genre_scores_gemma":[0.991743,0.0002717193,0.0002105344,0.0003156192,0.00008308858,0.0003153403,0.005769733,0.000009457389,0.00128148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002616432,"threshold_uncertainty_score":0.0136959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01796372547445917,"score_gpt":0.2777588634098017,"score_spread":0.2597951379353425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}