{"id":"W3212333063","doi":"10.25251/skin.5.supp.52","title":"Bimekizumab response maintenance through two years of treatment in patients with moderate to severe plaque psoriasis who responded after 16 weeks: Interim results from the BE BRIGHT open-label extension trial","year":2021,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Plaque psoriasis; Interim; Open label; Medicine; Psoriasis; Extension (predicate logic); Internal medicine; Dermatology; Interim analysis; Clinical trial; Surgery; History","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002919359,0.001032161,0.003448773,0.0002818263,0.0006130607,0.001794104,0.0008325945,0.001837303,0.0052657],"category_scores_gemma":[0.001825065,0.0005383514,0.002804786,0.0003302931,0.001006456,0.001725843,0.0005028553,0.004389449,0.001582384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007746539,"about_ca_system_score_gemma":0.0009090434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027371,"about_ca_topic_score_gemma":0.001696625,"domain_scores_codex":[0.9989725,0.000391524,0.00005006214,0.0001642816,0.00008023723,0.0003414047],"domain_scores_gemma":[0.9986801,0.0003096019,0.0002897633,0.0001626136,0.00007551938,0.0004824644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9535348,0.005510599,0.00187309,0.0004401732,0.001086263,0.00006977845,0.0001020108,0.000407555,0.003082224,0.0001399919,0.002734984,0.03101857],"study_design_scores_gemma":[0.8788574,0.1023797,0.01430759,0.00009410247,0.001122592,0.0001028965,0.00006716169,0.0004642484,0.0005649898,0.0003415174,0.001665496,0.00003219689],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862263,0.005522683,0.000529405,0.001343474,0.000474748,0.0008416277,0.001479037,0.0001343496,0.003448476],"genre_scores_gemma":[0.9889052,0.001616027,0.000758547,0.001775176,0.0004329872,0.001215719,0.001707624,0.00003555922,0.003553067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0052657,"threshold_uncertainty_score":0.01761556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02578579340508559,"score_gpt":0.280982458042791,"score_spread":0.2551966646377054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}