{"id":"W3212361944","doi":"10.1038/s41586-021-04083-0","title":"Host immunomodulatory lipids created by symbionts from dietary amino acids","year":2021,"lang":"en","type":"article","venue":"Nature","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Complementary and Integrative Health; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Bacteroides fragilis; Immune system; CD1D; Biology; Natural killer T cell; Amino acid; Effector; Cell; Receptor; Biochemistry; T cell; Cell biology; Microbiology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002276657,0.0004509124,0.0002360543,0.0003029405,0.0002502013,0.0005837106,0.0001585606,0.0004682995,0.001598526],"category_scores_gemma":[0.0001608425,0.0001745287,0.0002331977,0.0001238768,0.0003106244,0.0004286274,0.0006604959,0.0005911982,0.0003434989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002653783,"about_ca_system_score_gemma":0.0001867028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001736484,"about_ca_topic_score_gemma":0.0003290357,"domain_scores_codex":[0.9998635,0.00003570308,0.000005660485,0.00002067366,0.00003249221,0.00004197169],"domain_scores_gemma":[0.9998751,0.00002063136,0.00003830926,0.000009729155,0.00001682411,0.00003948889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005428167,0.000005328551,0.0004029546,0.00003821508,0.000008565316,0.000180312,0.00001853123,0.00003095705,0.9969814,0.0002310353,0.00001834522,0.001541539],"study_design_scores_gemma":[0.00006633689,0.0003830847,0.008519203,0.00002906419,0.00003872915,0.0005378071,0.0001490893,0.0004313219,0.984588,0.0007269293,0.004518969,0.00001158817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901782,0.004039317,0.002794205,0.000233723,0.00008381489,0.00001424688,0.0001077499,0.00003325143,0.00251557],"genre_scores_gemma":[0.9943004,0.00139623,0.00198328,0.00008952206,0.00003003797,0.00001379569,0.00009658175,0.00001888696,0.002071251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001598526,"threshold_uncertainty_score":0.00534761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005707155258063265,"score_gpt":0.2193383928708216,"score_spread":0.2136312376127583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}