{"id":"W3212446185","doi":"10.1242/dmm.048256","title":"Treatment of age-related visual impairment with a peptide acting on mitochondria","year":2021,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute on Aging; National Institutes of Health","keywords":"Photopic vision; Scotopic vision; Visual acuity; Medicine; Audiology; Visual impairment; Optokinetic reflex; Ophthalmology; Internal medicine; Physiology; Biology; Retinal; Eye movement","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001181336,0.0003536823,0.0003042493,0.0001486705,0.0000954251,0.0001717744,0.0001851009,0.0002856805,0.0007170601],"category_scores_gemma":[0.00009344459,0.00007030849,0.0002112543,0.00007900209,0.0001647895,0.0002265013,0.0001410553,0.0005358398,0.0001637886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000145677,"about_ca_system_score_gemma":0.0001273871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002556654,"about_ca_topic_score_gemma":0.0004729286,"domain_scores_codex":[0.999951,0.00000475858,0.000004988632,0.00001366634,0.00001016023,0.00001537671],"domain_scores_gemma":[0.9999412,0.00000873722,0.00002025386,0.000007206424,0.000008691031,0.00001385191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000155692,0.00005058441,0.000200791,0.00002884737,0.000004371085,0.00004981205,0.000008896678,0.00004595737,0.9969849,0.00003535367,0.00002124215,0.002413522],"study_design_scores_gemma":[0.00004595098,0.004088277,0.01473656,0.0000136372,0.00002906706,0.0005812381,0.0000289951,0.0005258001,0.9778126,0.00008669161,0.00204167,0.00000970295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957652,0.002129304,0.001187479,0.00006659402,0.00001965246,0.00003341399,0.0001446652,0.00004433416,0.0006092977],"genre_scores_gemma":[0.995016,0.001765951,0.001766771,0.00006746451,0.00001028172,0.00004315239,0.000196773,0.000007396879,0.001126183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007170601,"threshold_uncertainty_score":0.002398849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010630816784648,"score_gpt":0.2432421729312877,"score_spread":0.2331358647634413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}