{"id":"W3212446185","doi":"10.1242/dmm.048256","title":"Treatment of age-related visual impairment with a peptide acting on mitochondria","year":2021,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute on Aging; National Institutes of Health","keywords":"Photopic vision; Scotopic vision; Visual acuity; Medicine; Audiology; Visual impairment; Optokinetic reflex; Ophthalmology; Internal medicine; Physiology; Biology; Retinal; Eye movement","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000291992,0.0002038885,0.000171465,0.00003504102,0.00006364646,0.00001856827,0.00006690259,0.00006469914,0.00003368682],"category_scores_gemma":[0.00001017412,0.0001651674,0.0001329169,0.00008523204,0.0000266487,0.000004939189,0.00003690382,0.00003059762,0.000006017743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002946861,"about_ca_system_score_gemma":0.0002088639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000913064,"about_ca_topic_score_gemma":0.0000102362,"domain_scores_codex":[0.9989401,0.00004465336,0.0001839494,0.0003940478,0.0002120122,0.0002252507],"domain_scores_gemma":[0.9994307,0.000006768785,0.00007856817,0.0002444721,0.00007331907,0.0001662349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00424338,0.003841065,0.000698024,0.0001089824,0.0008036777,0.0007945105,0.0009375515,0.01077598,0.9605439,0.009828446,0.0002159111,0.007208534],"study_design_scores_gemma":[0.006564517,0.005487803,0.001674965,0.000178376,0.0003348598,0.00002202286,0.00120983,0.008169408,0.9598246,0.01457748,0.001038398,0.0009176926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854818,0.0002971004,0.01230182,0.0001179275,0.00007864748,0.0002789935,0.00001877057,0.00001858333,0.001406384],"genre_scores_gemma":[0.9957357,0.0001280284,0.002148459,0.00009112267,0.00002296451,0.00006558378,0.0004261578,0.00002836012,0.001353628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01025392,"threshold_uncertainty_score":0.6735329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010630816784648,"score_gpt":0.2432421729312877,"score_spread":0.2331358647634413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}