{"id":"W3212504456","doi":"10.1007/s11307-021-01672-3","title":"Visualizing CAR-T cell Immunotherapy Using 3 Tesla Fluorine-19 MRI","year":2021,"lang":"en","type":"article","venue":"Molecular Imaging and Biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Robarts Clinical Trials; Western University","funders":"","keywords":"Chimeric antigen receptor; CD19; Immunotherapy; Cancer research; Medicine; Magnetic resonance imaging; Bioluminescence imaging; Cancer cell; Antigen; T cell; Leukemia; Cancer; Chemistry; Pathology; Immunology; Internal medicine; Luciferase; Immune system; Radiology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002396359,0.000345473,0.0001532993,0.0003589479,0.0001451926,0.0003042792,0.0002172745,0.0005041574,0.001557033],"category_scores_gemma":[0.0001147131,0.0001998495,0.0001945879,0.0001339452,0.0002524054,0.0003079432,0.000152692,0.0004388863,0.0004193038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000214082,"about_ca_system_score_gemma":0.0002531426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008467206,"about_ca_topic_score_gemma":0.0008385106,"domain_scores_codex":[0.9999409,0.00001635631,0.000003874581,0.00001390211,0.00001136788,0.00001364448],"domain_scores_gemma":[0.9999213,0.00001941944,0.00002586135,0.000005471849,0.00001007338,0.00001773412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007035368,0.00001524141,0.0001984915,0.00003942255,0.000003319964,0.00009873358,0.00001157568,0.0001792266,0.9973884,0.0001238583,0.0001016526,0.001769694],"study_design_scores_gemma":[0.00004662898,0.0007608503,0.003170458,0.00002465543,0.00003650761,0.002138301,0.00004459819,0.004131318,0.9824399,0.000302794,0.006890242,0.00001369513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8414105,0.006126343,0.1406637,0.0007313943,0.00008455191,0.0002193459,0.0005337718,0.00112753,0.009102835],"genre_scores_gemma":[0.8711455,0.003289006,0.1195467,0.0003391855,0.00005162626,0.000158285,0.0003764432,0.0001023449,0.004990818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001557033,"threshold_uncertainty_score":0.005208731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03018635400214208,"score_gpt":0.3601495771999009,"score_spread":0.3299632231977588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}