{"id":"W3212504456","doi":"10.1007/s11307-021-01672-3","title":"Visualizing CAR-T cell Immunotherapy Using 3 Tesla Fluorine-19 MRI","year":2021,"lang":"en","type":"article","venue":"Molecular Imaging and Biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Robarts Clinical Trials; Western University","funders":"","keywords":"Chimeric antigen receptor; CD19; Immunotherapy; Cancer research; Medicine; Magnetic resonance imaging; Bioluminescence imaging; Cancer cell; Antigen; T cell; Leukemia; Cancer; Chemistry; Pathology; Immunology; Internal medicine; Luciferase; Immune system; Radiology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002290816,0.0001665576,0.0002966925,0.0001212528,0.0001009604,0.00004084404,0.00007108352,0.00008199125,0.000372553],"category_scores_gemma":[0.00004334571,0.0001511701,0.0001060819,0.0002253424,0.0001524838,0.0000248829,0.0001007723,0.0002448338,0.000007780649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000642095,"about_ca_system_score_gemma":0.0001631097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002197051,"about_ca_topic_score_gemma":0.000001225444,"domain_scores_codex":[0.9987177,0.0001735898,0.0001893894,0.0004102731,0.0001046882,0.0004043531],"domain_scores_gemma":[0.9993432,0.00005400242,0.00003916756,0.0003287449,0.000109159,0.0001257777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006154717,0.00005303035,0.01682371,0.00003809768,0.00006103274,0.0004562648,0.0001617429,0.00000245395,0.9539557,0.00007238456,0.000131358,0.02818273],"study_design_scores_gemma":[0.002066533,0.0001193307,0.0005753274,0.00003915328,0.00004246759,0.0009761929,0.0002208467,0.001540306,0.8740833,0.0002511058,0.1198681,0.000217248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9629044,0.02774962,0.004102041,0.001812146,0.0001692198,0.0001707624,0.000004960741,0.00006284376,0.003023996],"genre_scores_gemma":[0.9882481,0.001563605,0.004041971,0.003864243,0.0001773129,0.000008551306,0.00006307956,0.00005826883,0.001974929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1197368,"threshold_uncertainty_score":0.6164536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03018635400214208,"score_gpt":0.3601495771999009,"score_spread":0.3299632231977588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}