{"id":"W3212521911","doi":"10.1002/trc2.12202","title":"Dementia risk reduction: why haven't the pharmacological risk reduction trials worked? An in‐depth exploration of seven established risk factors","year":2021,"lang":"en","type":"article","venue":"Alzheimer s & Dementia Translational Research & Clinical Interventions","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital; McGill University; Douglas Mental Health University Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; Medical Research Council; Alzheimer's Society","keywords":"Reduction (mathematics); Dementia; Safe haven; Medicine; Haven; Internal medicine; Economics; Disease; Mathematics; Financial economics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.4293058,0.00157726,0.006913731,0.004460305,0.001994096,0.01158195,0.003488745,0.005740898,0.005412303],"category_scores_gemma":[0.5766638,0.001829141,0.005649581,0.005692443,0.005767335,0.01307152,0.003753413,0.006886813,0.0007292013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006762128,"about_ca_system_score_gemma":0.01443148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007031038,"about_ca_topic_score_gemma":0.01089589,"domain_scores_codex":[0.7009654,0.2326849,0.03405007,0.008771082,0.0210878,0.002440797],"domain_scores_gemma":[0.34447,0.5763494,0.0282913,0.01654138,0.03079054,0.003557459],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.007256733,0.0006538713,0.03512624,0.08127753,0.04439512,0.000275576,0.00488578,0.005869003,0.0008639815,0.06768154,0.03584037,0.7158743],"study_design_scores_gemma":[0.01153818,0.006485442,0.06520788,0.3285176,0.06070128,0.0009591802,0.006607077,0.01164566,0.002107687,0.3200278,0.1853464,0.0008558555],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02120962,0.5949444,0.02415058,0.343728,0.005882904,0.002347663,0.00155958,0.0001531054,0.006024064],"genre_scores_gemma":[0.4245947,0.2443864,0.08357032,0.2280697,0.009625315,0.006861625,0.001119766,0.0003621554,0.001410083],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5706942,"threshold_uncertainty_score":0.7037677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8401794758111385,"score_gpt":0.6117425900269085,"score_spread":0.22843688578423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}