{"id":"W3212524944","doi":"10.1080/14728222.2021.2006186","title":"Emerging therapeutic targets for idiopathic pulmonary fibrosis: preclinical progress and therapeutic implications","year":2021,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Medicine; Idiopathic pulmonary fibrosis; Disease; Clinical trial; Drug development; Therapeutic approach; Drug; Precision medicine; Bioinformatics; Intensive care medicine; Lung; Pharmacology; Internal medicine; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009661231,0.0006214349,0.001132416,0.001337811,0.0002163152,0.001290865,0.0007893465,0.001371486,0.006269418],"category_scores_gemma":[0.001105249,0.0001911167,0.0006975061,0.0009580814,0.0004144836,0.001208918,0.0006454539,0.002223606,0.002945273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005031296,"about_ca_system_score_gemma":0.001022544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005375409,"about_ca_topic_score_gemma":0.00121828,"domain_scores_codex":[0.9997266,0.00006169341,0.0000278733,0.00004127869,0.0001060384,0.00003650678],"domain_scores_gemma":[0.9994498,0.0002462878,0.00007390558,0.00001332297,0.0001703955,0.00004637644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001603755,0.0000850235,0.0001504072,0.02152916,0.0001036709,0.0002547315,0.00007832955,0.0004654338,0.004302339,0.006156742,0.04043614,0.9262776],"study_design_scores_gemma":[0.00004406903,0.0002387817,0.0006036141,0.006946841,0.0001435834,0.0009701551,0.00007072855,0.0001801746,0.0009703549,0.003220343,0.98659,0.00002145829],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001725754,0.9969982,0.0002308698,0.0008880449,0.0003766699,0.00001100816,0.00004495678,0.00001010111,0.001267562],"genre_scores_gemma":[0.001268242,0.9967269,0.0002868155,0.000587302,0.0002923191,0.00001492951,0.00008105765,0.000002653778,0.0007398209],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006269418,"threshold_uncertainty_score":0.02097332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07511358586126267,"score_gpt":0.4044528558500161,"score_spread":0.3293392699887534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}