{"id":"W3212563578","doi":"10.6084/m9.figshare.c.5657403","title":"Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer","year":2021,"lang":"en","type":"article","venue":"","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Enhancer; Epigenomics; Biology; Histone; Genetics; Single-nucleotide polymorphism; Chromatin; Computational biology; Acetylation; Chromatin immunoprecipitation; Transcription factor; Epigenetics; Enhancer RNAs; Gene; Gene expression; DNA methylation; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002669651,0.0001721095,0.0002512206,0.0005691178,0.00007779659,0.0002414314,0.0001689135,0.000174063,0.0006193314],"category_scores_gemma":[0.0002897893,0.0001416242,0.0002649106,0.0003119775,0.0001232088,0.0001097928,0.0002086996,0.0001850954,0.0001818171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000145548,"about_ca_system_score_gemma":0.00009443425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008615864,"about_ca_topic_score_gemma":0.002256088,"domain_scores_codex":[0.9998635,0.0000185525,0.000006535222,0.00005896145,0.00003207492,0.00002031636],"domain_scores_gemma":[0.9997995,0.00007587757,0.00004668845,0.00002761576,0.00002640822,0.00002383885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000256866,0.00002728993,0.06837596,0.0001053319,0.00008957517,0.00008137723,0.00008800656,0.001751497,0.9156064,0.000150403,0.0001319781,0.01333534],"study_design_scores_gemma":[0.00002037816,0.0002346602,0.7552986,0.00001530597,0.0002282351,0.00081423,0.0001414945,0.0292165,0.210668,0.0004129085,0.002925606,0.0000242022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932483,0.0004723574,0.004775755,0.00001344611,0.000001660808,0.000008204869,0.001082505,0.00009793164,0.0002998154],"genre_scores_gemma":[0.9945381,0.0001351639,0.003273735,0.00002063128,0.000002492625,0.00001219153,0.001706687,0.00002440276,0.0002865262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008615864,"threshold_uncertainty_score":0.002071857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01124603888626382,"score_gpt":0.2674949133063556,"score_spread":0.2562488744200918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}