{"id":"W3212566661","doi":"10.1182/blood-2021-153098","title":"PLAGL2 Independently Drives Aberrant Erythropoiesis and Initiation of Preleukemic State","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; McMaster University; Population Health Research Institute","funders":"","keywords":"Haematopoiesis; Erythropoiesis; Biology; Cancer research; Progenitor cell; CD34; Stem cell; Bone marrow; Leukemia; Malignancy; Myeloid; Immunology; Anemia; Medicine; Internal medicine; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008639718,0.0002556552,0.0001641986,0.0001658986,0.0001093411,0.0002552998,0.000166814,0.0002025508,0.001909077],"category_scores_gemma":[0.0000763588,0.00008255028,0.0001720727,0.000116814,0.0001957159,0.0001178544,0.0003370728,0.0005766398,0.000500515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003066027,"about_ca_system_score_gemma":0.0001235462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002662602,"about_ca_topic_score_gemma":0.000354528,"domain_scores_codex":[0.9998711,0.00001524862,0.00001132749,0.00003751176,0.00003396965,0.00003078252],"domain_scores_gemma":[0.9999046,0.00001234575,0.00002709927,0.00001413357,0.000008149218,0.00003371179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008289001,0.00001802787,0.000328696,0.00001734057,0.000002546847,0.00007533881,0.000006590576,0.00004725589,0.9989372,0.00006719644,0.00005227054,0.0003646788],"study_design_scores_gemma":[0.00001082038,0.0002134432,0.006938765,0.000004537217,0.00001103754,0.0004107714,0.00003143098,0.001112867,0.9880248,0.00008440527,0.003152502,0.000004581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942786,0.0004690097,0.00231735,0.00009995015,0.00002262766,0.00003375662,0.001306605,0.0001860466,0.001285963],"genre_scores_gemma":[0.9949201,0.000170923,0.000874732,0.00005524692,0.000006948307,0.00003697857,0.00126787,0.00002904791,0.002638149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001909077,"threshold_uncertainty_score":0.006386518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01483837085783916,"score_gpt":0.2714841318293106,"score_spread":0.2566457609714714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}