{"id":"W3212731641","doi":"10.1093/ibd/izab259","title":"Recommendations for Standardizing Clinical Trial Design and Endoscopic Assessment in Postoperative Crohn’s Disease","year":2021,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Western University","funders":"UCB Pharma; Allergan; Genentech; Akebia Therapeutics; Celltrion; AbbVie; Novo Nordisk; Teva Pharmaceutical Industries; Gilead Sciences; ActoGeniX; Sanofi; Celgene; Biogen; GlaxoSmithKline; National Institute of Diabetes and Digestive and Kidney Diseases; Tillotts Pharma; Amgen; Pfizer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Crohn's disease; Clinical trial; Placebo; Disease; Clinical endpoint; Internal medicine; Surgery; Physical therapy; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.7479158,0.004965472,0.009041762,0.01356722,0.005332309,0.01575145,0.01627265,0.05352629,0.005243573],"category_scores_gemma":[0.7552344,0.005375474,0.01690279,0.01470652,0.01423883,0.01266135,0.007538185,0.04292835,0.008815182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01105998,"about_ca_system_score_gemma":0.06305648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004829007,"about_ca_topic_score_gemma":0.006094257,"domain_scores_codex":[0.161911,0.6580611,0.1150758,0.008313213,0.05080047,0.005838466],"domain_scores_gemma":[0.1012379,0.4871579,0.07314704,0.06104456,0.2632876,0.01412492],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.006862568,0.001954524,0.006590975,0.04000951,0.002094471,0.0009463261,0.005685025,0.007256035,0.005233738,0.04435359,0.4222924,0.4567208],"study_design_scores_gemma":[0.01597927,0.004344508,0.01679189,0.1635738,0.005147367,0.001080552,0.002962264,0.01345983,0.006500948,0.07639642,0.692405,0.00135818],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.005961063,0.0625357,0.314999,0.4116128,0.04731577,0.1160847,0.003662573,0.004036488,0.03379191],"genre_scores_gemma":[0.01329346,0.009181062,0.8023154,0.09026004,0.006624541,0.07406399,0.001163424,0.0004894922,0.002608588],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.2520842,"threshold_uncertainty_score":0.3108647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03962439381982767,"score_gpt":0.3532102800103925,"score_spread":0.3135858861905648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}