{"id":"W3212847609","doi":"10.1016/s1473-3099(21)00327-3","title":"Efficacy, immunogenicity, and safety of a quadrivalent HPV vaccine in men: results of an open-label, long-term extension of a randomised, placebo-controlled, phase 3 trial","year":2021,"lang":"en","type":"article","venue":"The Lancet Infectious Diseases","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Catholic Medical Center; Meso Scale Diagnostics","keywords":"Phase (matter); Clinical trial; Extension (predicate logic); Human papillomavirus; Vaccination; Cancer vaccine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005556614,0.001830253,0.00318277,0.0004448309,0.0008050385,0.001333386,0.001194058,0.003278798,0.004675201],"category_scores_gemma":[0.005301693,0.0009432809,0.004004335,0.0005555646,0.002475048,0.002130782,0.0006464698,0.003757778,0.0008075589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001067247,"about_ca_system_score_gemma":0.001346224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001302344,"about_ca_topic_score_gemma":0.001141236,"domain_scores_codex":[0.997229,0.00166727,0.0001683168,0.0003945409,0.0002443561,0.0002964138],"domain_scores_gemma":[0.9954775,0.001927749,0.001026042,0.0005509859,0.0002820122,0.0007358591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9813151,0.006088865,0.000928809,0.0002468979,0.0007729379,0.00002276443,0.0001052787,0.000155354,0.002116238,0.00003607815,0.0001482099,0.008063559],"study_design_scores_gemma":[0.8198833,0.1720747,0.005883911,0.00003335522,0.0007650084,0.00003117721,0.00004282604,0.0002000279,0.0006350701,0.0001266884,0.000296361,0.00002754212],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930319,0.003187446,0.0004936621,0.0003558254,0.0002295889,0.001449754,0.0005420353,0.00005083187,0.0006589548],"genre_scores_gemma":[0.993822,0.001215462,0.0008230296,0.0005636078,0.0004049844,0.001489097,0.0006678436,0.00002158295,0.0009924195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005556614,"threshold_uncertainty_score":0.02938652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04904654839387583,"score_gpt":0.3878322969745744,"score_spread":0.3387857485806986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}