{"id":"W3212886181","doi":"10.1093/brain/awab419","title":"The neuroradiology of progressive multifocal leukoencephalopathy: a clinical trial perspective","year":2021,"lang":"en","type":"review","venue":"Brain","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"National Institutes of Health","keywords":"Progressive multifocal leukoencephalopathy; Neuroradiology; JC virus; Medicine; Clinical trial; Histopathology; Pathology; Neurology; Slow virus; Leukoencephalopathy; White matter; Magnetic resonance imaging; Radiology; Virus; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003424196,0.0006990743,0.002720991,0.001368298,0.0002032546,0.001437425,0.001236322,0.002021969,0.003911538],"category_scores_gemma":[0.005272288,0.0001970409,0.001234235,0.001556246,0.0004234062,0.001280628,0.0004122989,0.001878987,0.0009537221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006436678,"about_ca_system_score_gemma":0.001840543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006345224,"about_ca_topic_score_gemma":0.001401153,"domain_scores_codex":[0.9993531,0.0002847044,0.0001257586,0.00006800686,0.0001305941,0.00003775072],"domain_scores_gemma":[0.9964394,0.002587074,0.0003120658,0.00005853665,0.0004878917,0.0001150306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009955594,0.0001922015,0.0002546873,0.08130216,0.0006625331,0.0001662469,0.00007819751,0.0002663539,0.0007698319,0.003998207,0.01881518,0.8924989],"study_design_scores_gemma":[0.001727535,0.002186992,0.002709789,0.1339596,0.003461456,0.001706889,0.0001732624,0.0002712005,0.0007689905,0.004779582,0.8481899,0.00006467602],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001342004,0.9986427,0.00003911188,0.0004683653,0.0001537163,0.00001629275,0.00002024354,0.000003267868,0.0005220047],"genre_scores_gemma":[0.001896521,0.9964597,0.0001925623,0.0009033114,0.0002236618,0.00004914285,0.0000367777,0.000002310022,0.000235966],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003911538,"threshold_uncertainty_score":0.01810908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1584084981362457,"score_gpt":0.5138018632575905,"score_spread":0.3553933651213448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}