{"id":"W3212993705","doi":"10.1016/j.biomaterials.2021.121248","title":"Physiologic flow-conditioning limits vascular dysfunction in engineered human capillaries","year":2021,"lang":"en","type":"article","venue":"Biomaterials","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Division of Chemical, Bioengineering, Environmental, and Transport Systems; Natural Sciences and Engineering Research Council of Canada; Massachusetts Institute of Technology; National Sleep Foundation; National Science Foundation","keywords":"Microvessel; Endothelium; Hemodynamics; Blood flow; Angiogenesis; Cell biology; Biology; Pathology; Biomedical engineering; Cardiology; Internal medicine; Medicine; Cancer research","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179487,0.0001221095,0.0001644356,0.00003138851,0.00007690627,0.00004096948,0.00006564974,0.0001516242,0.00021271],"category_scores_gemma":[0.00004209296,0.0001164086,0.00008703498,0.00007869472,0.00003243473,0.000004315767,0.00004528483,0.000006896099,0.00001665147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001708614,"about_ca_system_score_gemma":0.0000382628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002117838,"about_ca_topic_score_gemma":0.00002724395,"domain_scores_codex":[0.9992053,0.0000734485,0.0001959773,0.0002807424,0.00006680023,0.0001777477],"domain_scores_gemma":[0.9996393,0.000004229574,0.0000475087,0.0002182489,0.00006051463,0.00003020144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001277499,0.00002775819,0.0004355466,0.00002230804,0.00004149415,0.000007375338,0.00001727579,0.0001130077,0.998266,0.00006598756,0.0007763921,0.0002140829],"study_design_scores_gemma":[0.0002958777,0.00005644906,0.01649238,0.00002004324,0.0000125911,0.000005738131,0.00003987489,0.000009223313,0.9745831,0.00007519549,0.008254317,0.000155158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970927,0.001932527,0.0002284074,0.00003104987,0.0004519921,0.0000753487,0.00003431622,0.00001925124,0.0001344627],"genre_scores_gemma":[0.9976868,0.0002880068,0.0003698753,0.0001294604,0.0004547044,0.0000390384,0.0008699337,0.00001672722,0.0001454424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02368284,"threshold_uncertainty_score":0.4747007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01671954226437079,"score_gpt":0.2522734791357596,"score_spread":0.2355539368713889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}