{"id":"W3212997076","doi":"10.3390/ijms222212232","title":"Angptl2 is a Marker of Cellular Senescence: The Physiological and Pathophysiological Impact of Angptl2-Related Senescence","year":2021,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Institut de Cardiologie de Montréal","keywords":"Senescence; Paracrine signalling; Proinflammatory cytokine; Chemokine; Biology; DNA damage; Inflammation; Autocrine signalling; Context (archaeology); Cell biology; Ageing; Cancer research; Immunology; Cell culture; Biochemistry; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008591379,0.0002623886,0.001315639,0.0002339948,0.00004307352,0.00003450992,0.0007185853,0.0001952995,0.0001249621],"category_scores_gemma":[0.0005370479,0.0001242571,0.001138741,0.0005177796,0.0009428416,0.0001022573,0.0002106426,0.0003780839,0.00000138597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000345054,"about_ca_system_score_gemma":0.001031541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001919551,"about_ca_topic_score_gemma":1.029971e-7,"domain_scores_codex":[0.9971502,0.0003523683,0.0009504747,0.0003000606,0.001059361,0.0001875257],"domain_scores_gemma":[0.9975508,0.0001866154,0.001213473,0.0002061062,0.0007258966,0.0001171507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002886481,0.001505359,0.001577783,0.002800738,0.00441602,0.001739129,0.0009116278,0.00006844389,0.2710134,0.001262811,0.001099783,0.7133163],"study_design_scores_gemma":[0.02714081,0.02940979,0.1134933,0.265653,0.0367814,0.0459008,0.008234579,0.003410626,0.05861466,0.01568047,0.3865051,0.00917549],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08928496,0.909679,0.0001566253,0.0001740157,0.0004061582,0.0001775413,0.00003284948,0.000003137815,0.00008570134],"genre_scores_gemma":[0.1663483,0.8329012,0.0004561733,0.0001451712,0.000110672,0.000002075082,0.00000960951,0.000008545702,0.00001823686],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7041408,"threshold_uncertainty_score":0.5067056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03793855324220385,"score_gpt":0.370448405465433,"score_spread":0.3325098522232291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}