{"id":"W3213065056","doi":"10.1016/j.ejps.2021.106058","title":"Development and pharmacokinetic evaluation of a self-nanoemulsifying drug delivery system for the oral delivery of cannabidiol","year":2021,"lang":"en","type":"article","venue":"European Journal of Pharmaceutical Sciences","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Mitacs","keywords":"Bioavailability; Cannabidiol; Pharmacokinetics; Pharmacology; Oral administration; Drug; Chemistry; Drug delivery; Absorption (acoustics); Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000274723,0.0002416202,0.0002617914,0.0002194,0.0001616329,0.0002193343,0.0001992492,0.0002572077,0.0004608042],"category_scores_gemma":[0.0002214229,0.0001730572,0.0002612207,0.0001236628,0.0001271807,0.0002563992,0.0001371926,0.0002838338,0.0002186034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000421977,"about_ca_system_score_gemma":0.0004483795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001982187,"about_ca_topic_score_gemma":0.001914005,"domain_scores_codex":[0.9999027,0.0000144779,0.000008989756,0.00002206425,0.00003672722,0.00001507946],"domain_scores_gemma":[0.9999222,0.0000108784,0.00002806982,0.000006493837,0.00002326095,0.000009167949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001134459,0.00005734586,0.0001155894,0.00005984967,0.000005050839,0.00003256534,0.00001383411,0.0001621775,0.9944917,0.00005628746,0.00003680935,0.004855314],"study_design_scores_gemma":[0.00003084967,0.0009787206,0.001443992,0.00000528239,0.00002518943,0.0001079823,0.00001125021,0.002621401,0.9919159,0.00001813656,0.002829469,0.00001181488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778893,0.002090688,0.01785002,0.0001382476,0.00004920315,0.0002619309,0.0003616351,0.0001379216,0.001221105],"genre_scores_gemma":[0.9556401,0.002772587,0.03667673,0.00007452695,0.00002386397,0.000261433,0.0005090453,0.00003689791,0.00400481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001982187,"threshold_uncertainty_score":0.003941357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1148995195581488,"score_gpt":0.3910544215466839,"score_spread":0.2761549019885351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}