{"id":"W3213131303","doi":"10.1016/j.mcpro.2021.100174","title":"Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases","year":2021,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"H2020 Excellent Science; European Regional Development Fund; Horizon 2020 Framework Programme; H2020 Spreading Excellence and Widening Participation; Grantová Agentura, Univerzita Karlova; Univerzita Karlova v Praze; Grantová Agentura České Republiky; Ministerstvo Školství, Mládeže a Tělovýchovy","keywords":"Lysosome; Secretion; Biology; Proteome; Phagolysosome; Cell biology; Biochemistry; Proteases; Secretory pathway; Glycosylation; Secretory protein; Endosome; Golgi apparatus; Endoplasmic reticulum; Phagosome; Phagocytosis; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006575448,0.0002266743,0.0006211182,0.0006223998,0.0001110161,0.00001930845,0.000174029,0.0002287877,0.0004579209],"category_scores_gemma":[0.0004568973,0.0002358234,0.0003619137,0.001367567,0.0004003544,0.0001094565,0.0001643969,0.0003361336,0.00001583803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000605834,"about_ca_system_score_gemma":0.0002174238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001663969,"about_ca_topic_score_gemma":0.000005736436,"domain_scores_codex":[0.997655,0.000628714,0.000646027,0.0005936567,0.0001646111,0.0003119359],"domain_scores_gemma":[0.9982721,0.00006524363,0.0003822729,0.0005319491,0.0007091197,0.0000393544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001430609,0.0004362387,0.01691081,0.0001437492,0.002289331,0.00003771277,0.0001056289,0.0004931113,0.9780449,0.00111265,0.00002034932,0.0002625163],"study_design_scores_gemma":[0.001037023,0.0002312087,0.007554062,0.00003231572,0.0007867765,0.00005112354,0.00006817732,0.000202996,0.9892615,0.0002877377,0.0002943641,0.0001927111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789955,0.003754045,0.01597086,0.0001003588,0.00009572727,0.0007206278,0.0001064847,0.00002626161,0.0002301359],"genre_scores_gemma":[0.9958706,0.00009484195,0.002195342,0.000009607416,0.00001938583,0.00009441098,0.0009928654,0.00002691823,0.0006960413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01687509,"threshold_uncertainty_score":0.9616598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009249045202623497,"score_gpt":0.2499641802191512,"score_spread":0.2407151350165277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}