{"id":"W3213131303","doi":"10.1016/j.mcpro.2021.100174","title":"Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases","year":2021,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"H2020 Excellent Science; European Regional Development Fund; Horizon 2020 Framework Programme; H2020 Spreading Excellence and Widening Participation; Grantová Agentura, Univerzita Karlova; Univerzita Karlova v Praze; Grantová Agentura České Republiky; Ministerstvo Školství, Mládeže a Tělovýchovy","keywords":"Lysosome; Secretion; Biology; Proteome; Phagolysosome; Cell biology; Biochemistry; Proteases; Secretory pathway; Glycosylation; Secretory protein; Endosome; Golgi apparatus; Endoplasmic reticulum; Phagosome; Phagocytosis; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001157961,0.0003308825,0.0003044519,0.0005019804,0.000184498,0.0002695901,0.0001148676,0.000208084,0.0003297413],"category_scores_gemma":[0.0001651739,0.00009768317,0.0003157869,0.0004467555,0.0001039776,0.000148145,0.0001874954,0.0001610885,0.0001897066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001711903,"about_ca_system_score_gemma":0.000189527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007339288,"about_ca_topic_score_gemma":0.0008000809,"domain_scores_codex":[0.9999166,0.000008143908,0.000009826765,0.00002127224,0.00002684325,0.00001737332],"domain_scores_gemma":[0.9999183,0.00001033545,0.00002137803,0.000006279012,0.00002185788,0.00002192389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008460449,0.000009595284,0.001066472,0.00008298061,0.00001289576,0.0001762921,0.00003468554,0.00002248009,0.9973394,0.00001512301,0.00002557018,0.001129815],"study_design_scores_gemma":[0.00002143404,0.0004001443,0.2234805,0.00005308625,0.0001858878,0.004497651,0.0005312385,0.002646236,0.7618998,0.0001439126,0.006108858,0.00003119271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936039,0.002321241,0.001528858,0.00006168425,0.00001502382,0.00003245464,0.001724645,0.00002786023,0.0006844384],"genre_scores_gemma":[0.9836263,0.003506002,0.006659744,0.0001122524,0.0000313825,0.00006659026,0.004027834,0.00003058769,0.001939276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007339288,"threshold_uncertainty_score":0.001459301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009249045202623497,"score_gpt":0.2499641802191512,"score_spread":0.2407151350165277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}