{"id":"W3213172814","doi":"10.1182/blood-2021-144421","title":"Sustained Improvement in Health-Related Quality of Life in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma Treated with Daratumumab, Lenalidomide, and Dexamethasone Versus Lenalidomide and Dexamethasone: Update of the Phase 3 MAIA Trial","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Alberta; University of Calgary","funders":"","keywords":"Lenalidomide; Dexamethasone; Daratumumab; Multiple myeloma; Medicine; Internal medicine; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008309823,0.0006937509,0.002290339,0.0003195702,0.0004420943,0.002193348,0.0007737915,0.0008134817,0.001930568],"category_scores_gemma":[0.00435277,0.0002640878,0.003226127,0.000753088,0.0005052798,0.0008250712,0.0007640808,0.002893659,0.0003068238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000606688,"about_ca_system_score_gemma":0.001023945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003841937,"about_ca_topic_score_gemma":0.001139957,"domain_scores_codex":[0.9978679,0.001372337,0.0002236889,0.0001579462,0.0002449685,0.000133144],"domain_scores_gemma":[0.9956422,0.001465236,0.001391712,0.0003463716,0.0004529277,0.000701501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6562116,0.006959894,0.05946769,0.004604447,0.02138202,0.0001609988,0.0004498596,0.001839539,0.007193632,0.0008906174,0.01069697,0.2301427],"study_design_scores_gemma":[0.5444521,0.1651334,0.2163353,0.002451167,0.02846501,0.0008618122,0.0003142731,0.002768487,0.003857302,0.00223204,0.03290325,0.000225927],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9096977,0.06784029,0.001818984,0.004113526,0.0008969462,0.003250163,0.006705285,0.0001059624,0.005571239],"genre_scores_gemma":[0.9604441,0.0163682,0.003720842,0.003204997,0.001277846,0.005334199,0.008379969,0.00004374621,0.001225994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008309823,"threshold_uncertainty_score":0.0439471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02593192923513089,"score_gpt":0.2995565192646997,"score_spread":0.2736245900295688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}