{"id":"W3213182364","doi":"10.1002/cbic.202100502","title":"Binding Methylarginines and Methyllysines as Free Amino Acids: A Comparative Study of Multiple Host Classes**","year":2021,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Division of Chemistry; Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft; National Science Foundation","keywords":"Cucurbituril; Binding affinities; Amino acid; Affinities; Chemistry; Binding selectivity; Host (biology); Stereochemistry; Selectivity; Methylation; Biochemistry; Biology; Organic chemistry; Supramolecular chemistry; Molecule; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004173283,0.0003630783,0.0004308915,0.0001768311,0.0001954388,0.0003559178,0.0003737652,0.0004289193,0.001228534],"category_scores_gemma":[0.0004442311,0.0001639197,0.0002449618,0.0002096751,0.0002504923,0.0004909612,0.0002867937,0.0002993014,0.0002516566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002999959,"about_ca_system_score_gemma":0.000139987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001117013,"about_ca_topic_score_gemma":0.001570624,"domain_scores_codex":[0.9997528,0.00004656772,0.00001083837,0.00004753095,0.00006979011,0.00007235781],"domain_scores_gemma":[0.9996946,0.0001495604,0.00003953195,0.00001948779,0.00004488134,0.00005189681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001784213,0.00002512574,0.0004428721,0.0001029117,0.00001089873,0.00003903755,0.00003896806,0.0002485447,0.9969073,0.0001039491,0.00002278675,0.001879201],"study_design_scores_gemma":[0.000008345572,0.000868938,0.005800532,0.000007333807,0.00002237638,0.0002628619,0.0001209543,0.003300585,0.9878668,0.00007532527,0.00164455,0.00002140855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931647,0.002962099,0.002578973,0.00003840851,0.000009137422,0.00001924955,0.0001069744,0.00002055528,0.001099844],"genre_scores_gemma":[0.9919383,0.002096029,0.004038026,0.00006134275,0.00001008543,0.00001696404,0.0002039979,0.00001244069,0.001622808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001228534,"threshold_uncertainty_score":0.004109859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02310507760581739,"score_gpt":0.2881108150173383,"score_spread":0.2650057374115209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}