{"id":"W3213182364","doi":"10.1002/cbic.202100502","title":"Binding Methylarginines and Methyllysines as Free Amino Acids: A Comparative Study of Multiple Host Classes**","year":2021,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Division of Chemistry; Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft; National Science Foundation","keywords":"Cucurbituril; Binding affinities; Amino acid; Affinities; Chemistry; Binding selectivity; Host (biology); Stereochemistry; Selectivity; Methylation; Biochemistry; Biology; Organic chemistry; Supramolecular chemistry; Molecule; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323877,0.000214221,0.0004477402,0.000044264,0.00006996792,0.00003252457,0.0002105294,0.0001333688,0.00004307462],"category_scores_gemma":[0.0005676121,0.0001952545,0.0001426608,0.0002772898,0.0001024487,0.000005487371,0.0003584583,0.00008615763,0.000003823589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009350031,"about_ca_system_score_gemma":0.00003674292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004973989,"about_ca_topic_score_gemma":0.00006713155,"domain_scores_codex":[0.9987425,0.00006505769,0.0002997056,0.0005193768,0.000173807,0.0001995377],"domain_scores_gemma":[0.9989421,0.00008653753,0.0001411172,0.0005202176,0.0002117842,0.00009821945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003876668,0.0004375857,0.01424304,0.00002964066,0.000385554,0.000005819641,0.0002974927,8.562648e-7,0.9840195,0.000008608209,0.000278521,0.000254586],"study_design_scores_gemma":[0.001022826,0.000141126,0.002704637,0.00001894125,0.0001606716,0.000007784492,0.004939976,0.00002206122,0.9895683,0.00002214452,0.001168322,0.0002232143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969579,0.001971955,0.00004706738,0.00009009967,0.00002879948,0.0001084342,0.00002649042,0.00001044948,0.0007588329],"genre_scores_gemma":[0.9980923,0.0001400276,0.0008900824,0.00003612288,0.0001001271,0.00002108258,0.00008979114,0.00001739581,0.0006130814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0115384,"threshold_uncertainty_score":0.7962245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02310507760581739,"score_gpt":0.2881108150173383,"score_spread":0.2650057374115209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}