{"id":"W3213313371","doi":"10.3390/pr9112007","title":"Liquid Chromatography Tandem Mass Spectrometric Analytical Method for Study of Colchicine in Rats Given Low Doses","year":2021,"lang":"en","type":"article","venue":"Processes","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chromatography; Chemistry; Formic acid; Colchicine; Ammonium acetate; Urine; Detection limit; Extraction (chemistry); Electrospray ionization; Tandem mass spectrometry; Quantitative analysis (chemistry); Whole blood; High-performance liquid chromatography; Mass spectrometry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007125665,0.00143612,0.0009833341,0.00166171,0.0007121745,0.000339234,0.0005967274,0.001086458,0.002043716],"category_scores_gemma":[0.0008291672,0.0004050666,0.0003310201,0.000910616,0.0004888276,0.0003860038,0.0003109501,0.001270971,0.001184354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007077786,"about_ca_system_score_gemma":0.001318581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001961272,"about_ca_topic_score_gemma":0.005481065,"domain_scores_codex":[0.9992383,0.0001528182,0.00004118812,0.0001834108,0.0003235186,0.00006083605],"domain_scores_gemma":[0.9992529,0.0001270328,0.0001638305,0.0000611584,0.0002941239,0.0001010914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002326629,0.00006072639,0.0005779027,0.0000782368,0.00002261692,0.00006840695,0.00001460666,0.00005152578,0.9933581,0.00006371219,0.0002095134,0.005261962],"study_design_scores_gemma":[0.00007323913,0.001391571,0.01083516,0.00002594467,0.00009694941,0.0008804153,0.00002975076,0.00230759,0.9784232,0.0001024207,0.005775629,0.00005817733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4656527,0.01783105,0.4841812,0.00119222,0.001008603,0.002202859,0.006306905,0.008591864,0.01303264],"genre_scores_gemma":[0.6199902,0.009663239,0.340254,0.00222559,0.0003198429,0.005105339,0.003159488,0.0003909361,0.01889141],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002043716,"threshold_uncertainty_score":0.006836951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02503571180334535,"score_gpt":0.3360026793934391,"score_spread":0.3109669675900938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}