{"id":"W3213387284","doi":"10.1182/blood-2021-144454","title":"Nonmyeloablative HLA-Identical Sibling Donor Transplantation for Children and Young Adults with Sickle Cell Disease: Interim Results of the SUN Multicenter Phase II Trial","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; Hospital for Sick Children","funders":"","keywords":"Medicine; Alemtuzumab; Hematopoietic stem cell transplantation; Total body irradiation; Transplantation; Regimen; Internal medicine; Pediatrics; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002039314,0.0005245426,0.001311301,0.0001292353,0.0002651246,0.0007401857,0.0004608016,0.0004399685,0.001718237],"category_scores_gemma":[0.000866809,0.0001598287,0.001302534,0.0002240922,0.0003888301,0.0004028124,0.0002744379,0.001269315,0.0001750776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005698337,"about_ca_system_score_gemma":0.001388646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008724382,"about_ca_topic_score_gemma":0.00382181,"domain_scores_codex":[0.9995413,0.0002430912,0.00003261789,0.00005471583,0.00006067381,0.00006769582],"domain_scores_gemma":[0.9991346,0.0001859185,0.0002226117,0.00006110137,0.00005778786,0.0003380399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7655369,0.01374813,0.06272182,0.001687347,0.005469798,0.0003869772,0.0002987711,0.0021396,0.009367842,0.0005705639,0.009334845,0.1287374],"study_design_scores_gemma":[0.6999114,0.1895275,0.09682462,0.000265781,0.003181562,0.0008024545,0.0001416494,0.001431594,0.002604902,0.0004845634,0.004783767,0.00004017241],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919404,0.004465795,0.000208482,0.0003266566,0.0000853974,0.0005797881,0.001212019,0.00002490979,0.001156626],"genre_scores_gemma":[0.989988,0.003226598,0.001065779,0.0007437886,0.0001614374,0.0009829495,0.003016783,0.00001073513,0.000803917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002039314,"threshold_uncertainty_score":0.01078504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006959898951671165,"score_gpt":0.2504574193770873,"score_spread":0.2434975204254162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}