{"id":"W3213387284","doi":"10.1182/blood-2021-144454","title":"Nonmyeloablative HLA-Identical Sibling Donor Transplantation for Children and Young Adults with Sickle Cell Disease: Interim Results of the SUN Multicenter Phase II Trial","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; Hospital for Sick Children","funders":"","keywords":"Medicine; Alemtuzumab; Hematopoietic stem cell transplantation; Total body irradiation; Transplantation; Regimen; Internal medicine; Pediatrics; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001000486,0.0001181699,0.000198878,0.0000372706,0.0001070758,0.00001434136,0.00004614073,0.0000658724,0.00001028199],"category_scores_gemma":[0.0001179687,0.00007409696,0.00009520727,0.0001297943,0.00008438935,0.00005773629,0.00002326358,0.0001248411,5.357475e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006999069,"about_ca_system_score_gemma":0.00008723554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004035602,"about_ca_topic_score_gemma":0.00005080941,"domain_scores_codex":[0.9990842,0.00004138176,0.0003097408,0.0002467295,0.0001592718,0.0001586712],"domain_scores_gemma":[0.9994529,0.00006275714,0.0001067475,0.0001627319,0.0001125608,0.0001023076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8651598,0.02814241,0.02934705,0.00228035,0.001609497,0.0002946685,0.02755358,0.00004582985,0.03714609,0.0001058056,0.0005568262,0.007758103],"study_design_scores_gemma":[0.8464091,0.006032678,0.03744949,0.001663417,0.003948523,0.00009487011,0.001858228,0.0009320687,0.101169,0.00002219028,0.0001148462,0.0003055533],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971164,0.0004123989,0.0002142819,0.0004669725,0.0001236199,0.001144671,0.0003105124,0.00001466788,0.0001964618],"genre_scores_gemma":[0.9987018,0.000205021,0.0004293802,0.00005511682,0.00008145854,0.00002232657,0.0002441921,0.000016066,0.0002446841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06402293,"threshold_uncertainty_score":0.3021586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006959898951671165,"score_gpt":0.2504574193770873,"score_spread":0.2434975204254162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}