{"id":"W3213709497","doi":"10.1038/s41392-021-00779-x","title":"Roles and mechanisms of exosomal non-coding RNAs in human health and diseases","year":2021,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":397,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Fundamental Research Funds for the Central Universities; Central South University; National Natural Science Foundation of China","keywords":"Microvesicles; microRNA; Exosome; Biology; Computational biology; Circular RNA; Biomarker; Diagnostic biomarker; Long non-coding RNA; Non-coding RNA; Bioinformatics; RNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001373864,0.0002625938,0.0006583648,0.0001029759,0.00008330281,0.0000239354,0.00006762151,0.0001818236,0.00003084179],"category_scores_gemma":[0.000005415164,0.0002419544,0.0001396378,0.00009825617,0.0001180429,0.000006552671,0.00002227553,0.0001352527,8.898687e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009079494,"about_ca_system_score_gemma":0.0001351935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009119687,"about_ca_topic_score_gemma":0.000007479462,"domain_scores_codex":[0.9986996,0.0002082324,0.0003684303,0.0004481166,0.00009882759,0.0001767845],"domain_scores_gemma":[0.9994947,0.00001244835,0.0001508566,0.0001506018,0.00002560555,0.0001657853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009863234,0.0002635822,0.00006011758,0.005534383,0.0003104166,0.00001695205,0.0002148957,0.000001901625,0.1399001,0.001184112,0.00002537022,0.8523895],"study_design_scores_gemma":[0.01331422,0.006071926,0.0008319741,0.02433811,0.001203037,0.0005828531,0.002570772,0.00008085599,0.268141,0.009651211,0.6685654,0.00464866],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007579722,0.9895207,0.00236448,0.00002435404,0.00004950598,0.0003677109,0.00007769449,0.000006916715,0.000008877536],"genre_scores_gemma":[0.05945655,0.9397557,0.0001851194,0.00004389862,0.00008673078,0.00002791246,0.0003854337,0.0000340186,0.00002460647],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8477408,"threshold_uncertainty_score":0.9866616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02292044452079976,"score_gpt":0.3076912217555403,"score_spread":0.2847707772347405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}