{"id":"W3213758112","doi":"10.5267/j.ccl.2021.9.003","title":"Synthesis and biological evaluation of some new 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as antimicrobial agents","year":2021,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Research Foundation; National Research Foundation of Ukraine","keywords":"Antimicrobial; Chemistry; Staphylococcus aureus; Candida albicans; Cryptococcus neoformans; Acinetobacter baumannii; Klebsiella pneumoniae; Pseudomonas aeruginosa; Escherichia coli; Microbiology; Klebsiella pneumonia; Bacteria; Organic chemistry; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003267312,0.0002739426,0.0004241131,0.00001793157,0.00007484077,0.00004340367,0.0002170471,0.0002303302,0.003700213],"category_scores_gemma":[0.001667894,0.0002251151,0.0001936073,0.0001111959,0.0001945395,0.00008702141,0.0001594414,0.0002337632,0.00002222045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007669141,"about_ca_system_score_gemma":0.0001304068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001528311,"about_ca_topic_score_gemma":2.74522e-7,"domain_scores_codex":[0.9982696,0.00007545634,0.000369888,0.0006080055,0.0003650874,0.0003120056],"domain_scores_gemma":[0.9988316,0.0003338224,0.0002183506,0.0003321128,0.0001160409,0.0001680999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000396542,0.0002044723,0.008746956,0.0001727249,0.00006537919,0.000006974627,0.00002726653,0.000003809521,0.9514161,0.000006362353,0.001277191,0.03803305],"study_design_scores_gemma":[0.0005382615,0.000001877189,0.00493191,0.0001668182,0.0001401109,0.00002913257,0.00003063627,0.00006548763,0.991731,0.0001237942,0.001960777,0.0002801232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959804,0.000888082,0.000006618032,0.002222178,0.0001600808,0.00006168063,0.00006189833,0.00005000451,0.0005690781],"genre_scores_gemma":[0.9985703,0.0004668571,0.00008085902,0.0001602599,0.00058031,0.00001874613,0.00008918487,0.00001279037,0.0000206473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04031492,"threshold_uncertainty_score":0.9972106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08483222121195935,"score_gpt":0.3050988509378046,"score_spread":0.2202666297258453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}