{"id":"W3213817406","doi":"10.1182/blood-2021-148652","title":"Impact of Allogeneic Hematopoietic Cell Transplantation (HCT) As Consolidation Following CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy for Treatment of Relapsed Acute Lymphoblastic Leukemia (ALL)","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Chimeric antigen receptor; Hematopoietic cell; Medicine; Hematopoietic stem cell transplantation; Transplantation; Hematologic Neoplasms; Acute lymphocytic leukemia; CD19; Immunology; Cancer research; Antigen; Lymphoblastic Leukemia; Leukemia; Oncology; Haematopoiesis; Stem cell; Internal medicine; T cell; Biology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007077192,0.0001177371,0.0001802063,0.0001595943,0.0001207498,0.0003915878,0.000196739,0.0001006106,0.0009424682],"category_scores_gemma":[0.001375847,0.00004768651,0.000289189,0.0002266869,0.0001700544,0.0001790404,0.0002907712,0.0003449768,0.00007487935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004717748,"about_ca_system_score_gemma":0.0006488697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001003374,"about_ca_topic_score_gemma":0.001993434,"domain_scores_codex":[0.9996107,0.0001831165,0.00003200146,0.00005188504,0.00007184437,0.00005035886],"domain_scores_gemma":[0.9990318,0.0002760725,0.0004486397,0.00003746926,0.00004506012,0.0001610023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006017032,0.0005218365,0.9161105,0.0001001968,0.0003289555,0.0002779554,0.00006010897,0.001901122,0.002184135,0.000243901,0.0006254402,0.07162899],"study_design_scores_gemma":[0.0002999317,0.006523801,0.9829916,0.00006300073,0.0005801235,0.0008481714,0.0001362434,0.003972493,0.002650858,0.0001191924,0.001808392,0.000006155343],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983526,0.0008369149,0.0001588175,0.00009081922,0.000009613894,0.00001117341,0.0001097377,0.00000618732,0.0004240162],"genre_scores_gemma":[0.9995317,0.000157103,0.00006556645,0.00002363559,0.00000990332,0.000003751267,0.0001367622,9.736715e-7,0.0000705658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001003374,"threshold_uncertainty_score":0.003742814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01989192779643441,"score_gpt":0.3112064418056722,"score_spread":0.2913145140092378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}