{"id":"W3213907938","doi":"10.1016/s2468-1253(21)00294-6","title":"Etrolizumab versus infliximab for the treatment of moderately to severely active ulcerative colitis (GARDENIA): a randomised, double-blind, double-dummy, phase 3 study","year":2021,"lang":"en","type":"article","venue":"The Lancet. Gastroenterology & hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"F. Hoffmann-La Roche; Roche","keywords":"Double blind; Ulcerative colitis; Infliximab; Medicine; Internal medicine; Gardenia; Gastroenterology; Double blind study; Traditional medicine; Dermatology; Placebo; Tumor necrosis factor alpha; Pathology; Disease; Traditional Chinese medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001825926,0.001455011,0.0036334,0.0004133317,0.0004658199,0.001187477,0.0009945021,0.00288967,0.006526922],"category_scores_gemma":[0.001638716,0.0008270374,0.002544241,0.0004398479,0.00127283,0.001185683,0.0004662992,0.002855096,0.001001914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000624809,"about_ca_system_score_gemma":0.0008416733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001340316,"about_ca_topic_score_gemma":0.002283019,"domain_scores_codex":[0.9993212,0.0003750227,0.00005095298,0.0000865398,0.00004412233,0.0001221572],"domain_scores_gemma":[0.9989184,0.0004271014,0.0002011578,0.00008426042,0.00005922635,0.0003099429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9886143,0.002061561,0.0001646427,0.0004462874,0.0005287987,0.00003407324,0.00002692507,0.0001329501,0.001386718,0.00004854432,0.0002829205,0.006272234],"study_design_scores_gemma":[0.9697353,0.0286441,0.000808009,0.00002076268,0.0002277821,0.00002142958,0.00001139777,0.0001137757,0.000119106,0.00006118347,0.0002283985,0.000008834597],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811794,0.00968815,0.0009153017,0.001034885,0.001232846,0.002752458,0.00107008,0.0001450086,0.001981838],"genre_scores_gemma":[0.9818345,0.00534896,0.001661578,0.002000833,0.0008952317,0.003065489,0.0008977774,0.00003356131,0.004262039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006526922,"threshold_uncertainty_score":0.02183473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04717041392585142,"score_gpt":0.3312742166730299,"score_spread":0.2841038027471785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}